Metastasis
Write To Karl Loren About This Page
Cancer & Biopsy
| |
|
Metastasis
is the action of a cancer that has been relatively inactive in a
relatively fixed location, for some reason, usually suddenly,
starting to spread throughout the body. The most common
reason for Metastasis would be surgery which cuts into the
cancer, usually in an effort to cut it all out, where the result is that some part of the cancer was NOT cut out and now
that the protective wall around the formerly inactive, or
slow-growing cancer is disrupted, cancer cells enter into the
blood stream, are carried to other parts of the body, and then
start growing as new cancers in those locations.
- Results for your query in Medline on July 11, 2000:
- Search all fields for: metastasis And biopsy
And spread
- Published in 1966 through 1999
- Only select references with abstracts available
- Show references published in English only
Documents: 1 to 100 of 243
|
Top Of Menu
|
|
|
Clinical
| Non-clinical
| Boston
University | Physician's
World | HealthStream
| Reuters
Medical | Newswire
| Doody's
Book Review | Software
Reviews | Blackwell
Science | Munksgaard
| Your
Health | Your
Lifestyle | Your
Research | MedGate
Member Login
We subscribe to the HONcode
principles
of the Health On the Net
Foundation
Send comments to support@healthgate.com
Copyright
© 2000 HealthGate® Data Corp.
|
|
Return To Top
NLM database Documents
Record 1 from database: MEDLINE
Return
To Top
- Title
- Implantation metastasis after percutaneous transthoracic needle
aspiration biopsy.
- Author
- Sinner WN; Zajicek J
- Address
-
- Source
- Acta Radiol [Diagn] (Stockh), 1976 Jul, 17:4, 473-80
- Abstract
- The risk of tumour spread at aspiration biopsy of pulmonary tumours
through the needle track has been analyzed by reviewing the case
histories of 1 264 patients with a malignant tumour demonstrated by
needle biopsy. Only in one case did metastatic tumour growth develop at
the site of the biopsy. The history of this case is presented and the
available literature on the subject discussed.
- Language of Publication
- English
- Unique Identifier
- 77018915
Return
To Top
- MeSH Heading (Major)
- Biopsy, Needle|*AE; Carcinoma, Squamous Cell|*/PA/RA; Lung Neoplasms|*/PA/RA;
Neoplasm Seeding|*
- MeSH Heading
- Aged; Case Report; Follow-Up Studies; Human; Lung|PA; Male; Neoplasm
Metastasis
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0567-8056
- Country of Publication
- SWEDEN
Record 2 from database: MEDLINE
Return
To Top
- Title
- Aspiration cytology for diagnosis of head and neck masses.
- Author
- Meyers DS; Templer J; Davis WE; Balch JA
- Address
-
- Source
- Otolaryngology, 1978 Jul, 86:4 Pt 1, ORL-650-5
- Abstract
- Most American clinicans have been relectant to utilize aspiration
biopsy due to poor interpretive skills by the pathologists in the past
and a fear of tumor spread by the needle. Voluminous European series and
recent American series have proved aspiration to be safe and reliable.
In our series of 78 cases, both thin-needle aspiration and conventional
tissue biopsies were made. The diagnoses were compared and the overall
agreement rate was 90%.
- Language of Publication
- English
- Unique Identifier
- 79245956
Return
To Top
- MeSH Heading (Major)
- Biopsy|*MT; Biopsy, Needle|*MT; Head and Neck Neoplasms|*PA
- MeSH Heading
- Carcinoma, Squamous Cell|PA; Comparative Study; Diagnostic Errors;
Human; Neoplasm Metastasis
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0161-6439
- Country of Publication
- UNITED STATES
Record 3 from database: MEDLINE
Return
To Top
- Title
- Diagnosis of lymphangitic carcinomatosis by transbronchial lung
biopsy.
- Author
- Torrington KG; Hooper RG
- Address
-
- Source
- South Med J, 1978 Dec, 71:12, 1487-8
- Abstract
- The records of patients who had transbronchial lung biopsy at Walter
Reed Army Medical Center between January 1974 and September 1977 were
retrospectively reviewed. Nine patients were found whose clinical and
radiographic presentations were compatible with lymphangitic
carcinomatosis. In five patients in lymphangitic spread of carcinoma was
diagnosed from transbronchial lung biopsy specimens. A single patient
had a false-negative biopsy, proven at autopsy three weeks later. The
other three patients with negative biopsies are alive and receiving
chemotherapy 12 months later (two patients) or are lost to follow-up
(one patient). Transbronchial lung biopsy is an accurate procedure for
diagnosing lymphangitic carcinomatosis. In addition, aggressive
chemotherapy should not be used in these patients without a tissue
diagnosis.
- Language of Publication
- English
- Unique Identifier
- 79076778
Return
To Top
- MeSH Heading (Major)
- Carcinoma|*PA; Lung|*PA; Lung Neoplasms|*PA; Lymphangitis|*PA
- MeSH Heading
- Biopsy|MT; Bronchoscopy; Fiber Optics; Human; Neoplasm Metastasis;
Retrospective Studies
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0038-4348
- Country of Publication
- UNITED STATES
Record 4 from database: MEDLINE
Return
To Top
- Title
- Techniques for inhibiting tumor metastases.
- Author
- Hoover HC Jr; Ketcham AS
- Address
-
- Source
- Cancer, 1975 Jan, 35:1, 5-14
- Abstract
- Of the four major biological mechanisms of cancer spread, hematogenous
dissemination is perhaps the most significant, as it usually heralds a
fatal outcome for the patient. Recent experimental approaches have shown
ways of altering the metastatic process and even totally inhibiting it
in some animal models. It appears that these models may be applicable to
certain human cancers. To prevent hematogenous metastasis formation the
process must be inhibited at any one of four levels: 1) growth of the
primary; 2) invasion of vessel walls; 3) release of viable tumor cells;
or 4) entrapment and growth in distant organs. Judicious handling of the
primary can decrease metastasis by minimizing the shedding of tumor
cells. New experimental agents prevent the release of tumor cells from
the primary by normalizing the blood vessels of the tumor. Warfarin,
heparin, and fibrinolytic agents inhibit the entrapment of circulating
tumor cells, presumably by their effect on coagulative mechanisms. A
better understanding of the benefits of combined approaches to cancer
using chemotherapy, irradiation, and immunotherapy, alone and as
adjuncts to surgery, offers new opportunity to study methods of
controlling metastatic disease.
- Language of Publication
- English
- Unique Identifier
- 75074060
Return
To Top
- MeSH Heading (Major)
- Neoplasm Circulating Cells|*PC; Neoplasm Metastasis|*; Neoplasms|RT/*TH
- MeSH Heading
- Animal; Antineoplastic Agents|TU; Biopsy; Cell Adhesion; Cell
Movement; Detergents|TU; Formaldehyde|AA/TU; Heparin|TU; Human;
Immunotherapy; Mice; Mice, Inbred Strains; Neoplasms, Experimental|SU/TH;
Pharmaceutic Aids; Piperazines|TU; Polyethylene Glycols|TU; Propane|AA/TU;
Rats; Rats, Inbred Strains; Warfarin|TU
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0008-543X
- Country of Publication
- UNITED STATES
Record 5 from database: MEDLINE
Return
To Top
- Title
- Liver tumors in children in the particular reference to hepatoblastoma
and hepatocellular carcinoma: American Academy of Pediatrics Surgical
Section Survey--1974.
- Author
- Exelby PR; Filler RM; Grosfeld JL
- Address
-
- Source
- J Pediatr Surg, 1975 Jun, 10:3, 329-37
- Abstract
- A review of 227 cases of hepatoblastoma, hepatic cell carcinoma in
children seen in the United States over a 10-yr period is presented.
Both tumors were seen most commonly in infancy, but the hepatocellular
carcinoma shows a second peak of incidence around puberty. Males
predominated in both diseases more so in hepatoblastoma. Presenting
symptoms in both diseases were very similar, most commonly an upper
abdominal mass or abdominal enlargement associated with anorexia and
weight loss. In the preoperative evaluation the presence of alpha-feto
protein was one of the most helpful diagnostic tests. Disturbances of
liver function were usually mild but were more marked in those children
with hepatocellular carcinoma. Preoperative x-rays were abnormal in a
large percentage of cases with the hepatic arteriogram and vena cavagram
being the most useful diagnostic x-rays for liver tumors. Liver scans
were positive for liver tumor in 95% of the children when this test was
carried out. The follow-up for these patients ranged from 2 to 10 yr.
The size of the primary tumor did not appear to correlate with survival
but bilateral location of the tumor, 33% in hepatoblastoma and 45% in
hepatocellular carcinoma, made many of these tumors inoperable.
Multicentric tumors were also found in a large number of patients, being
more common in hepatocellular carcinoma. There was a high rate of local
recurrence or local extension after operation in both diseases, and
metastatic spread was similar being most common to the lungs and
abdomen. A wide variety of surgical procedures were carried out in these
patients from biopsy only to extended hepatic lobectomy. When incomplete
excision or biopsy only was carried out no patient survived in either
group. Among the hepatoblastoma patients, 45 of 78 patients who had
complete excision are surviving. In the hepatocellular carcinoma
patients where the operability rate was much lower 12 of 33 patients are
surviving when tumor was completely excised. Complications were
frequent, the most common being excessive blood loss at operation. There
were eight operative deaths and 17 postoperative deaths in the combined
group. There was no evidence that radiation therapy or chemotherapy
controlled disease which could not be completely excised surgically. The
only direct evidence of a favorable effect of radiation and chemotherapy
were three cases of hepatoblastoma in which the tumor changed from
inoperable to operable by a combination of radiation therapy and
multiple drug chemotherapy. Both tumors are highly malignant, and 90% of
the children who died of hepatoblastoma died within 12 mo of diagnosis.
In the hepatocellular carcinoma 80% of the deaths occurred within 1 yr
of diagnosis. At this time it seems that operative excision offers the
only chance of cure in children with these tumors and cure rates of 60%
can be expected with hepatoblastoma and 33% in hepatocellular carcinoma
if the tumor can be completely excised.
- Language of Publication
- English
- Unique Identifier
- 75191344
Return
To Top
- MeSH Heading (Major)
- Carcinoma, Hepatocellular|*/PA/TH; Liver Neoplasms|*/PA/TH
- MeSH Heading
- alpha-Fetoproteins|AN; Adolescence; Angiography; Biopsy; Child; Child,
Preschool; Female; Human; Infant; Infant, Newborn; Liver|PA/RA/SU; Male;
Neoplasm Metastasis; Neoplasm Recurrence, Local; Postoperative
Complications; Radionuclide Imaging
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0022-3468
- Country of Publication
- UNITED STATES
Record 6 from database: MEDLINE
Return
To Top
- Title
- Staging laparotomy in the treatment of metastatic melanoma of the
lower extremities.
- Author
- Cohen MH; Schour L; Felix EL; Bernstein AD; Chretien PB; Rosenberg SA;
Ketcham AS
- Address
-
- Source
- Ann Surg, 1975 Dec, 182:6, 710-4
- Abstract
- Twenty-six consecutive patients with melanoma of the lower extremities
metastatic to the superficial inguinal lymph nodes were subjected to
laparotomy. No patient had preoperative evidence of tumor dissemination
past the superficial inguinal nodes. However three patients (12%) had
metastases to the liver or para-aortic lymph nodes documented at
laparotomy and were not subjected to iliac and obturator lymph node
dissection. One of these patients had concomitant local recurrence of
melanoma at the ankle. The other two patients had superficial inguinal
lymph nodes at least 5 cm in diameter, although two other such patients
with similar 5 cm lymph nodes did not have positive intra-abdominal
findings. The remaining 23 of the 26 patients underwent ipsilateral
iliac and obturator lymph node dissection, which proved positive in 3/23
patients (13%). Of these 23 patients undergoing iliac and obturator node
dissection, 18 had clinically positive (and microscopically positive)
superficial inguinal nodes prior to their dissection, while the
remaining 5 patients had clinically negative (but microscopically
positive) superficial inguinal nodes. The three cases of positive
dissected iliac and obturator nodes occurred among the 18 patients with
clinically positive superficial inguinal nodes (17%). Among the 5
patients with clinically negative, microscopically positive superficial
groin nodes, there was no detectable deep inguinal nodal spread (or
hepatic or para-aortic involvement).
- Language of Publication
- English
- Unique Identifier
- 76060602
Return
To Top
- MeSH Heading (Major)
- Leg|*; Lymph Nodes|*PA; Melanoma|*PA/SU
- MeSH Heading
- Adolescence; Adult; Aged; Biopsy; Case Report; Child; Female; Human;
Laparotomy; Liver Neoplasms|PA/SU; Lymph Node Excision; Lymphatic
Metastasis; Male; Middle Age; Neoplasm Metastasis
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0003-4932
- Country of Publication
- UNITED STATES
Record 7 from database: MEDLINE
Return
To Top
- Title
- Dissemination of cancer: the need for stimulation of the immune
process during the immunosuppression produced by major operations.
- Author
- Cole WH
- Address
-
- Source
- South Med J, 1982 Dec, 75:12, 1479-86
- Abstract
- There are four mechanisms of the dissemination of cancer: direct
extension by tissue planes, by lymphatics, by the vascular system, and
by implantation. Implantation may be either spontaneous or iatrogenic,
and the unique cases of spontaneous implantation reported by Beahrs, in
which carcinoma of the colon had seeded a fresh hemorrhoidectomy wound,
illustrate how hardy cancer cells can be. The factors affecting the
spread of cancer appear even more important than the mechanisms
themselves. Immunologic factors (including stimulation),
immunosuppression, tumor enhancement, tumor inhibition, and contrasting
features are important. Stimulation of the immune process is becoming
important because so many chemicals or processes are immunosuppressive,
and it is now evident that all, or practically all, major operations are
immunosuppressive. Accordingly, at the time of operation for cancer the
patient should be given something to stimulate his immune system during
the three or four weeks it is being suppressed by the operation.
- Language of Publication
- English
- Unique Identifier
- 83067685
Return
To Top
- MeSH Heading (Major)
- Immune Tolerance|*; Immunization|*; Neoplasm Invasiveness|*/DI;
Neoplasm Metastasis|*; Neoplasms|IM/*SU
- MeSH Heading
- Antineoplastic Agents|AE; Biopsy|AE; Biopsy, Needle|AE; Colonic
Neoplasms|SU; Female; Human; Lymphatic Metastasis|PC; Neoplasm
Circulating Cells; Neoplasm Seeding
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0038-4348
- Country of Publication
- UNITED STATES
Record 8 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Lung cancer diagnosis: evaluation of diagnostic techniques.
- Author
- Healy TM; Borrie J
- Address
-
- Source
- N Z Med J, 1975 May, 81:539, 423-4
- Abstract
- In 200 patients with histologically proven lung cancer, retrospective
analysis of the relative diagnostic value of sputum cytology, bronchial
washings cytology, bronchial biopsy, scalene node biopsy,
mediastinoscopy and thoracotomy was undertaken. Bronchial biopsy proved
positive in 80 percent of patients with central tumours (those lying
between the origin of a main brochus and the origins of lobar segmental
bronchi) against 35 percent of patients with peripheral tumours (those
lying distal to the origins of the lobar segmental bronchi). Sputum
cytology was positive in 27 percent of patients so investigated and
bronchial washings cytology in 14 percent--both techniques being more
effective with central tumours. Thoracotomy, as the sole method of
obtaining histological confirmation of the clinical diagnosis, accounted
for 20.5 percent of all cases, being used more often in patients with
peripheral tumours. In 15 percent the first histologically positive
result came from distal spread. The relative indications for needle
biopsy and endobronchial fibroscopy are discussed.
- Language of Publication
- English
- Unique Identifier
- 76011247
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Lung Neoplasms|*DI/SU
- MeSH Heading
- Biopsy; Bronchi|PA; Bronchoscopy; Comparative Study; Cytodiagnosis;
Evaluation Studies; Female; Human; Lymph Nodes|PA; Male; Mediastinoscopy;
Neoplasm Metastasis; Pleural Effusion|CY; Retrospective Studies;
Sputum|CY; Thoracic Surgery; Thorax|SU
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0028-8446
- Country of Publication
- NEW ZEALAND
Record 9 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Chemosurgery for skin cancer: fixed tissue and fresh tissue
techniques.
- Author
- Mohs FE
- Address
-
- Source
- Arch Dermatol, 1976 Feb, 112:2, 211-5
- Abstract
- Complete microscopical control of the excision of cancer of the skin
is achieved by removing tissues layer by layer and examining the
undersurface of each layer by means of frozen sections. If the cancer is
extensive and complicated or if it is of a type readily spread over an
excisional surface, the tissues are fixed in situ with zinc chloride
prior to excision (chemosurgery, fixed tissue technique). If the cancer
is not too extensive or complicated, the tissues are excised in the
fresh, unfixed state (chemosurgery, fresh tissue technique). Both
techniques are highly reliable; for example, in two consecutive series
of basal cell carcinomas treated chemosurgically, the five-year rate of
cure was 99.3% for the 9,351 lesions removed by the fixed tissue
technique and 97% for the 127 lesions removed by the fresh tissue
technique.
- Language of Publication
- English
- Unique Identifier
- 76276623
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Carcinoma, Basal Cell|PA/*SU; Ear Neoplasms|*SU; Facial Neoplasms|*SU;
Skin Neoplasms|PA/*SU
- MeSH Heading
- Biopsy; Ear, External|SU; Eyelid Neoplasms|PA/SU; Eyelids|PA;
Histocytochemistry; Human; Neoplasm Metastasis; Neoplasm Recurrence,
Local|SU; Staining
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0003-987X
- Country of Publication
- UNITED STATES
Record 10 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Scalpel excision of primary cutaneous malignant melanomas without
metastasis.
- Author
- Castrow FF 2d; Chernosky ME
- Address
-
- Source
- J Dermatol Surg Oncol, 1979 Feb, 5:2, 109-11
- Abstract
- Views and opinions about surgical treatment of primary malignant
melanomas that are without local spread or metastasis are presented. An
attempt is made to determine the limitations of office-based
dermatologists in the treatment of malignant melanomas of this stage.
Using accepted criteria for clinical recognition of malignant melanomas
early, it is suggested that surgical excisions of small malignant
melanomas that are judged to be complete obviate preliminary biopsies
and furnish surgical specimens that can be read histopathologically for
confirmation of clinical diagnosis and adequacy of excision.
- Language of Publication
- English
- Unique Identifier
- 79110131
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Melanoma|CL/PA/*SU; Skin Neoplasms|CL/PA/*SU
- MeSH Heading
- Biopsy; Follow-Up Studies; Human; Neoplasm Metastasis
- Publication Type
- JOURNAL ARTICLE
- Country of Publication
- UNITED STATES
Record 11 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Primary liposarcoma of bone.
- Author
- Larsson SE; Lorentzon R; Boquist L
- Address
-
- Source
- Acta Orthop Scand, 1975 Dec, 46:6, 869-76
- Abstract
- A case is presented of a rare primary liposarcoma of bone localized to
the major trochanter of the left femur of a 52-year-old female. Despite
combined treatment with curettage and irradiation with a total dose of
4,500 rad the neoplasm showed rapid invasive growth with destruction of
the bone, spread to the iliac fossa and outgrowth through the operation
wound. Approximately 5 months after admission the patient succumbed due
to widespread metastases in the lungs, liver and left kidney. The
histopathology, clinical course and treatment of this rare neoplasm of
the bone are discussed.
- Language of Publication
- English
- Unique Identifier
- 76108497
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Femoral Neoplasms|*/PA/RA; Liposarcoma|*/PA/RA
- MeSH Heading
- Biopsy; Case Report; Female; Femur|PA; Human; Lung Neoplasms; Middle
Age; Neoplasm Metastasis
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0001-6470
- Country of Publication
- DENMARK
Record 12 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Well-differentiated peripheral cholangiocarcinoma with an unusual
clinical course.
- Author
- Foucar E; Kaplan LR; Gold JH; Kiang DT; Sibley RK; Bosl G
- Address
-
- Source
- Gastroenterology, 1979 Aug, 77:2, 347-53
- Abstract
- A patient with an unresectable well-differentiated bile duct tumor who
survived for 15 yr after biopsy diagnosis is presented. Histologic
examination of the tumor revealed bland features of bile duct adenoma
despite extensive spread within the liver. Over its subsequent course,
the tumor progressively replaced the liver, achieving huge size,
although there was no evidence of metastases until shortly before the
patient's death. This clinical course was very unusual for either bile
duct adenoma or cholangiocarcinoma, but would be more characteristic of
another tumor of intrahepatic bile duct origin, the biliary cystadenoma.
However, this latter diagnosis was excluded with both gross and
microscopic pathologic criteria. Evidence is presented to support
classification of this tumor as an unusual varient of peripheral
cholangiocarcinoma which requires correlation of the clinical and
pathologic findings for correst diagnosis.
- Language of Publication
- English
- Unique Identifier
- 79192471
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Adenoma, Bile Duct|*DI/PA/UL; Bile Duct Neoplasms|*DI/PA/UL
- MeSH Heading
- Adult; Anemia|ET; Basement Membrane|UL; Biopsy; Case Report;
Desmosomes|UL; Epithelium|UL; Female; Gallbladder|PA; Human; Laparoscopy;
Laparotomy; Liver|PA; Lung Neoplasms; Microvilli|UL; Neoplasm
Metastasis; Pain; Palpation; Time Factors
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0016-5085
- Country of Publication
- UNITED STATES
Record 13 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Gastrointestinal carcinoma: diagnosis, staging, and follow-up.
- Author
- Nelson RS
- Address
-
- Source
- Geriatrics, 1976 Sep, 31:9, 83-5
- Abstract
- When cancer of the gastrointestinal tract is suspected, thorough
studies should be made to determine the presence, type, and severity of
the primary tumor and whether it has spread. Besides routine x-ray
studies, angiography, scanning, and sonography may furnish valuable
information. Endoscopy, which has revolutionized diagnosis of these
tumors, not only makes it possible to obtain a specimen for histologic
analysis without laparotomy but also reveals gross involvement as a
guide to surgery. Staging of the lesion helps the physician select which
patients would benefit from surgery and which instead should be treated
with palliative chemotherapy or irradiation, or both. The patient's
quality of life during treatment also must be considered. The side
effects of multiple-agent chemotherapy, for example, may take too great
a toll on the patient's ability to function. Continuous, long-term
follow-up is essential. Metastases may develop after three to five years
in particularly indolent tumors, and new primary lesions are far from
rare.
- Language of Publication
- English
- Unique Identifier
- 76258593
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Gastrointestinal Neoplasms|*DI/PA/SU
- MeSH Heading
- Biopsy; Follow-Up Studies; Human; Neoplasm Metastasis; Prognosis
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0016-867X
- Country of Publication
- UNITED STATES
Record 14 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Diagnostic imaging in cancer.
- Author
- Berman CG; Clark RA
- Address
- Department of Radiology, University of South Florida, Tampa.
- Source
- Prim Care, 1992 Dec, 19:4, 677-713
- Abstract
- Screening chest radiographs do not reduce mortality from lung
cancer. Should an incidental noncalcified pulmonary parenchymal nodule
be discovered, chest CT will demonstrate one third of such patients
to, in fact, have the multiple nodules of metastatic disease. CT is
very helpful to guide fine needle aspiration biopsy of lung lesions
and to assist in evaluation for resectability. MR can be helpful in
special circumstances, including the definition of the extent of
paravertebral, superior sulcus, and diaphragmatic lesions. Endorectal
ultrasound is not sensitive enough to function as a screening tool for
prostate cancer but is used routinely to guide biopsies. CT and MR are
rarely helpful in staging this disease. Given the highly
characteristic trait of bone metastasis in prostate cancer, a bone
scan is mandatory in all patients. Double contrast barium enema can be
used as an adjunct or alternative to sigmoidoscopy for colorectal
cancer screening, in the preoperative evaluation of patients, and in
postoperative surveillance. CT and MR can detect macroscopic
adenopathy and liver metastases; CT is generally the preferred study.
Screening mammography can have a major impact in reducing breast
cancer mortality. It is recommended that a baseline study be obtained
at age 35. Annual or biannual examinations should commence at age 40.
Any palpable lesion, whether or not it is demonstrated
mammographically, must be subjected to biopsy. Ultrasound is the most
useful initial imaging study for evaluating pelvic masses. MR will, on
occasion, identify the origin of a mass not determinable from
ultrasound scan. MR is particularly valuable to identify parametrial
spread (inoperability) of cervical cancer, and has been underused for
this purpose. Surgery remains the mainstay for the staging of ovarian
and endometrial cancer, although CT can be helpful to identify
macroscopic relapse, ascites, or liver metastases. Bone scan and liver
CT remain the standard procedures for detecting metastases in these
respective organ systems. MR can be invaluable in the imaging of
epidural metastasis and spinal cord compression in patients with
vertebral metastatic disease. Contrast-enhanced MR is more sensitive
than contrast-enhanced CT for detecting brain metastases, but the
latter remains a useful tool. Chest CT can improve the detection of
pulmonary metastases when this is of crucial importance.
- Language of Publication
- English
- Unique Identifier
- 93101764
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Diagnostic Imaging|*MT; Lung Neoplasms|*DI/PA/TH; Neoplasm
Metastasis|*DI/PA
- MeSH Heading
- Biopsy, Needle|MT; Breast Neoplasms|DI/PA; Colorectal Neoplasms|DI/SU;
Human; Male; Neoplasm Staging; Prostatic Neoplasms|DI/EP/MO;
Tomography, X-Ray Computed; United States
- Publication Type
- JOURNAL ARTICLE; REVIEW; REVIEW, ACADEMIC
- ISSN
- 0095-4543
- Country of Publication
- UNITED STATES
Record 15 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Extraperitoneal pelvioscopy: a new aid in staging of lower urinary
tract tumors. A preliminary report.
- Author
- Hald T; Rasmussen F
- Address
-
- Source
- J Urol, 1980 Aug, 124:2, 245-8
- Abstract
- A new technique to obtain biopsy specimens from the pelvic lymph
nodes is presented. A mediastinoscope introduced through a small
incision in the abdominal wall allows the identification of the pelvic
nodes. A series of 12 patients with prostatic or bladder carcinoma is
presented and the feasibility of the method is documented. There was
no morbidity associated with the endoscopic node biopsy. Suggestions
for modification of the instrument are made. The method is now under
further scrutiny to establish its place among other available methods
to study lymphogenous spread of pelvic malignancies.
- Language of Publication
- English
- Unique Identifier
- 80251874
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Bladder Neoplasms|*PA; Neoplasm Staging|IS/*MT
- MeSH Heading
- Aged; Biopsy|IS; Female; Human; Lymph Nodes|PA; Lymphatic
Metastasis|PA; Male; Middle Age
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0022-5347
- Country of Publication
- UNITED STATES
Record 16 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- Scope and value of bone marrow biopsies in metastatic cancer.
- Author
- Frisch B; Bartl R; Mahl G; Burkhardt R
- Address
-
- Source
- Invasion Metastasis, 1984, 4 Suppl 1:, 12-30
- Abstract
- The results of examination of 1,810 bone marrow biopsies of 1,725
patients with known or suspected carcinomas are presented. The
frequency of positive biopsies was 72% for unknown primaries, 42% for
mammary, 32% for prostatic, 14% for pulmonary and 19% for other
cancers; the overall rate of detection of metastases was 35%. The mode
of spread, the grade of tumour cell differentiation and the host
response to the presence of the metastases were investigated by light
and electron microscopic studies and by means of antibody reactions on
fresh-frozen sections. The results are presented and their relevance
to the fundamental understanding of the metastatic process is
outlined. Implications for clinical oncology and patient management
are discussed.
- Language of Publication
- English
- Unique Identifier
- 85181957
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Bone Marrow|*PA; Bone Neoplasms|IM/PA/*SC; Neoplasm Metastasis|*PA
- MeSH Heading
- Biopsy; Cell Differentiation; Human; Neoplasm Staging; Support,
Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0251-1789
- Country of Publication
- SWITZERLAND
Record 17 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
- Title
- 165 renal carcinomas: accuracy of imaging for diagnosis and
spread--cost efficiency.
- Author
- Plainfosse MC; Delecoeullerie G; Vital JL; Paty E; Merran S
- Address
-
- Source
- Eur J Radiol, 1983 May, 3:2, 132-7
- Abstract
- Based on a study of 165 cases of renal carcinoma, we compare the
relative diagnosis efficiency of different methods: intravenous
urography (IVU), ultrasound (U.S.), arteriography and computed
tomography (C.T.). Our evidence enables us to assert the excellent
diagnostic accuracy of ultrasound and the superiority of computed
tomography for good staging of renal carcinoma. The cost efficient
methods for the evaluation of this tumour are intravenous urography
(to show and localize the renal mass), ultrasound (to assert the
echogenic structure) and computed tomography (to establish the
diagnosis of carcinoma and judge its spread).
- Language of Publication
- English
- Unique Identifier
- 83261902
Return
To Top
Return
To Menu Position #10
- MeSH Heading (Major)
- Kidney Neoplasms|*DI/EC/PA
- MeSH Heading
- Angiography; Biopsy, Needle; Comparative Study; Cost-Benefit
Analysis; Diagnostic Errors; Human; Neoplasm Metastasis; Neoplasm
Staging; Tomography, X-Ray; Tomography, X-Ray Computed; Ultrasonics|DU;
Urography
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0720-048X
- Country of Publication
- GERMANY, WEST
Record 18 from database: MEDLINE
Return
To Top
Return
To Menu Position #10
Return
To Menu Position #20
- Title
- Detection of haematologic and nonhaematologic cancer by bone biopsy.
- Author
- Burkhardt R; Frisch B; Bartl R; Kettner G; Schlag R; Hill W
- Address
-
- Source
- Cancer Detect Prev, 1981, 4:1-4, 619-27
- Abstract
- A retrospective study was carried out to test the efficacy of
routine bone marrow biopsies for the diagnosis, classification, and
prognosis of different forms of neoplastic involvement. Trephine and
needle biopsies of the iliac crest of 3,626 patients with haematologic
and 838 patients with nonhaematologic neoplasias were embedded without
prior decalcification. 43 histologic variables were evaluated in
3-millimicrons sections of each biopsy, stained by five different
techniques. The incidence of bone marrow involvement, in decreasing
order of frequency, was as follows: plasmacytoma 55% and 95% of 428
cases, malignant lymphoma 37% and 79% of 1.112 cases, metastatic
carcinoma 20% and 63% of 838 cases, and Hodgkin disease 3% and 28% of
772 cases each without and with manifest systemic dissemination. In
the group of the metastatic carcinomas, there was a striking incidence
of bone marrow involvement--82%--due to occult primary tumours. From a
comparison of these figures with those reported in the literature, it
is concluded that the large variations in positive and negative
results are due to 1) differences in the size and the preparation of
the specimens, 2) extent of the neoplastic dissemination at the time
of the biopsy, and 3) the incidence of bone marrow involvement
characteris
