|
Record 1 from database: MEDLINE
 Return
To Top
- Title
- Associations of smoking, alcohol and physical activity
with risk factors for coronary heart disease and diabetes
in the first follow-up cohort of the Heart Disease and
Diabetes Risk Indicators in a Screened Cohort study
(HDDRISC-1).
- Author
- Godsland IF; Leyva F; Walton C; Worthington M; Stevenson
JC
- Address
- Wynn Department of Metabolic Medicine, Imperial College
School of Medicine, London, UK.
- Source
- J Intern Med, 1998 Jul, 244:1, 33-41
- Abstract
- OBJECTIVES: To investigate the associations between risk
factors for cardiovascular disease and cigarette smoking,
alcohol intake, and physical activity in a group of
predominantly healthy men. DESIGN: Cohort study with
baseline characterisation, clinical follow-up, and
identification of predictors of coronary artery disease
and diabetes. SETTING: University hospital metabolic day
ward. SUBJECTS: Participants in a company health programme
(n=742). MAIN OUTCOME MEASURES: Routine haematology and
biochemistry, cholesterol, triglycerides, high density
lipoprotein (HDL) cholesterol (on a subset of 522
subjects), and glucose and insulin levels during a 3 h
oral glucose tolerance test (OGTT). RESULTS: Independent
associations with previous cigarette smoking included high
uric acid and low HDL cholesterol, and with current
cigarette smoking, high haemoglobin and white cell count
and low OGTT insulin. Increasing alcohol intake was
associated with increasing blood pressure, uric acid, HDL
cholesterol and fasting glucose. The moderate range of
exercise intensity in this cohort was associated with
decreasing systolic blood pressure, fasting insulin and
OGTT glucose and insulin. Factor analysis distinguished
principal factors comprising features of the metabolic
syndrome with low physical activity, and high white cell
count, high haemoglobin concentration and low HDL
cholesterol with increasing previous and current cigarette
smoking and alcohol intake. CONCLUSIONS: Some
characteristics of the metabolic syndrome were seen with
previous but not current smoking habit. Regular alcohol
consumption was associated with mainly unfavourable
metabolic characteristics, although there was an
independent beneficial association with HDL cholesterol.
The improved metabolic syndrome profile seen with
increasing exercise is consistent with even moderate
degrees of physical activity having beneficial effects on
metabolism.
- Language of Publication
- English
- Unique Identifier
- 98361487
Return
To Top
- MeSH Heading (Major)
- Alcohol Drinking|*AE; Coronary Disease|*ET; Diabetes
Mellitus|*ET; Exercise|*; Smoking|*AE
- MeSH Heading
- Adult; Aged; Blood Glucose; Blood Pressure; Factor
Analysis, Statistical; Follow-Up Studies; Health Behavior;
Human; Linear Models; Lipoproteins, HDL Cholesterol|BL;
Male; Middle Age; Predictive Value of Tests; Prospective
Studies; Risk Factors; Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0954-6820
- Country of Publication
- ENGLAND
Record 2 from database: MEDLINE
Return
To Top
- Title
- Interactions between diabetes and family history of
coronary heart disease and other risk factors for coronary
heart disease among adults with diabetes in Utah.
- Author
- Schumacher MC; Hunt SC; Williams RR
- Address
- Department of Internal Medicine, University of Utah
School of Medicine, Salt Lake City 84108.
- Source
- Epidemiology, 1990 Jul, 1:4, 298-304
- Abstract
- We used a unique data base containing medical family
history information from representative Utah families to
investigate interactions between diabetes and family
history of coronary heart disease and other risk factors
for coronary heart disease. We compared nonrelated
individuals reported to have had diabetes mellitus
diagnosed over the age of 19 (948) with 2150 nondiabetic
individuals. Among both men and women, diabetes and family
history of early coronary heart disease magnified the risk
for coronary heart disease, so that in diabetic
individuals with a positive family history of coronary
heart disease, about 74% of the coronary heart disease
could be attributed to interaction. Relative to
nondiabetics without a family history of early coronary
heart disease, nondiabetics with family history had a
relative risk of 4.5 (2.3-8.7), diabetics without a family
history had a relative risk of 2.8 (1.6-4.9), and
diabetics with a family history had a relative risk of
21.3 (9.1-50.0). Smoking also interacted with diabetes;
among smoking diabetics, 47% of early heart disease may be
attributable to interaction between smoking and diabetes.
Smoking entailed the highest risk for diabetic women.
Hypertension and diabetes appeared to act additively, with
little interaction. Among women, family history of
diabetes was a risk factor for coronary heart disease with
a relative risk of 2.5 (1.0-6.4), whereas for men the
relative risk was estimated to be 0.4 (0.2-1.1).
- Language of Publication
- English
- Unique Identifier
- 91191033
Return
To Top
- MeSH Heading (Major)
- Coronary Disease|*ET/GE; Diabetes Mellitus|*CO/GE
- MeSH Heading
- Adult; Age Factors; Comparative Study; Female; Human;
Hypertension|CO; Male; Middle Age; Risk Factors; Sex
Factors; Smoking|AE; Support, Non-U.S. Gov't; Support,
U.S. Gov't, P.H.S.; Utah
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 1044-3983
- Country of Publication
- UNITED STATES
Record 3 from database: MEDLINE
Return
To Top
- Title
- Family history of coronary heart disease is a stronger
predictor of coronary heart disease morbidity and
mortality than family history of non-insulin dependent
diabetes mellitus.
- Author
- Kekäläinen P; Sarlund H; Pyörälä K; Laakso M
- Address
- Department of Medicine, Kuopio University Hospital,
Finland.
- Source
- Atherosclerosis, 1996 Jun, 123:1-2, 203-13
- Abstract
- The aim of this study was to compare the effect of
family history of non-insulin dependent diabetes mellitus
(NIDDM) and coronary heart disease (CHD) as risk factors
for CHD morbidity and mortality. Altogether, 394 siblings
of NIDDM probands and non-diabetic probands, with and
without CHD, were followed for 8 years with respect to CHD
events in a prospective population-based study. The
baseline study was conducted from 1983 to 1985. Age- and
sex-adjusted cumulative occurrence of CHD events was
higher in the siblings of the probands with CHD and with
NIDDM (13.1%; P = 0.037) and in the siblings of the
probands with CHD and without NIDDM (15.4%; P = 0.054),
compared with the siblings of the probands without NIDDM
and without CHD (4.8%). The incidence of fatal CHD events
tended to be higher in a group with a family history of
NIDDM and CHD, but the trend was not statistically
significant. In univariate logistic regression analyses, a
family history of CHD was positively associated with
cumulative occurrence of CHD events (odds ratio 2.53, P =
0.009), whereas a family history of NIDDM had no
significant association (odds ratio 1.39, P = 0.312).
After adjustment for age, sex, family history of NIDDM and
major cardiovascular risk factors, the association between
family history of CHD and cumulative occurrence of CHD
events remained significant (odds ratio 2.25, P = 0.048).
In conclusion, the present study indicates that a family
history of CHD is a stronger predictor of future CHD
events than a family history of NIDDM.
- Language of Publication
- English
- Unique Identifier
- 96377002
Return
To Top
- MeSH Heading (Major)
- Coronary Disease|*EP/GE; Diabetes Mellitus,
Non-Insulin-Dependent|*EP/GE
- MeSH Heading
- Aged; Body Mass Index; Cholesterol|BL; Female;
Finland|EP; Follow-Up Studies; Glucose Tolerance Test;
Human; Lipoproteins|BL; Logistic Models; Male; Middle Age;
Nuclear Family; Prospective Studies; Risk Factors;
Support, Non-U.S. Gov't; Survival Rate; Triglycerides|BL
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0021-9150
- Country of Publication
- IRELAND
Record 4 from database: MEDLINE
Return
To Top
- Title
- The Rochester Coronary Heart Disease Project: effect of
cigarette smoking, hypertension, diabetes, and steroidal
estrogen use on coronary heart disease among 40- to
59-year-old women, 1960 through 1982 [see comments]
- Author
- Beard CM; Kottke TE; Annegers JF; Ballard DJ
- Address
- Section of Clinical Epidemiology, Mayo Clinic,
Rochester, MN 55905.
- Source
- Mayo Clin Proc, 1989 Dec, 64:12, 1471-80
- Abstract
- A population-based case-control study of coronary heart
disease (CHD) risk in young women attributable to
cigarette smoking, hypertension, diabetes, and steroidal
estrogen use was conducted among residents of Rochester,
Minnesota. All newly diagnosed cases of CHD (sudden
unexpected death [SUD], N = 18; myocardial infarction
[MI], N = 90; and angina, N = 133) among female Rochester
residents 40 to 59 years of age during the years 1960
through 1982 were identified, and two community control
subjects were matched for age and duration of community
medical record. The overall adjusted odds ratio (OR) for
the association between steroidal estrogen use and
definite CHD (MI and SUD) was 0.6 (95% confidence interval
[CI] = 0.2 to 1.3). Smoking (OR = 5.1; 95% CI = 2.3 to
11.6), hypertension (OR = 4.8; 95% CI = 2.3 to 10.2), and
diabetes (OR = 8.4; 95% CI = 1.6 to 44.5) were strong risk
factors for CHD events. If considered causal, cigarette
smoking accounted for 64% of all MIs and SUDs in the
community, hypertension accounted for 45%, and diabetes
accounted for 13%. Although steroidal estrogen exposure
reduced CHD among these women by 14%, giving steroidal
estrogens to all women in this age group might reduce the
population rates of MI by as much as 45%.
- Language of Publication
- English
- Unique Identifier
- 90097220
Return
To Top
- MeSH Heading (Major)
- Coronary Disease|BL/EP/*ET/MO/PC; Diabetes Mellitus|*CO;
Estrogen Replacement Therapy|*; Estrogens, Conjugated|*TU;
Hypertension|*CO/PC; Smoking|*AE/BL/PC
- MeSH Heading
- Adult; Analysis of Variance; Bias (Epidemiology);
Cholesterol|BL; Comparative Study; Confounding Factors
(Epidemiology); Evaluation Studies; Female; Human;
Menopause; Middle Age; Minnesota; Retrospective Studies;
Risk Factors; Support, U.S. Gov't, P.H.S.; Time Factors
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0025-6196
- Country of Publication
- UNITED STATES
Record 5 from database: MEDLINE
Return
To Top
- Title
- The association of body fat distribution with
hypertension, hypertensive heart disease, coronary heart
disease, diabetes and cardiovascular risk factors in men
and women aged 18-79 years.
- Author
- Gillum RF
- Address
-
- Source
- J Chronic Dis, 1987, 40:5, 421-8
- Abstract
- To confirm the reported association of body fat
distribution with cardiovascular disease, diabetes, blood
pressure and serum cholesterol, data from the 1960-62
Health Examination Survey were analyzed. In this sample
drawn from the noninstitutionalized population of the
United States aged 18-79, mean values of two indices of
upper versus lower body fat distribution increased
steadily with age. Men had higher values than women, and
black women had higher values than white women. Higher
values of the indices were significantly associated with
higher blood pressure, post-load serum glucose and greater
prevalence of definite hypertension and definite
hypertensive heart disease independent of multiple
confounders. Associations with higher serum cholesterol
and definite coronary heart disease prevalence were
independent of overall ponderosity but not of age and
multiple other confounders. Greater abdominal relative to
lower body fat deposits were independently associated with
increased cardiovascular risk in men and women, blacks and
whites.
- Language of Publication
- English
- Unique Identifier
- 87166547
Return
To Top
- MeSH Heading (Major)
- Adipose Tissue|*AH; Anthropometry|*; Cardiovascular
Diseases|*EP; Coronary Disease|*EP; Diabetes Mellitus|*EP;
Heart Diseases|*EP; Hypertension|*EP
- MeSH Heading
- Adolescence; Adult; Age Factors; Aged; Blood Pressure;
Cholesterol|BL; Comparative Study; Cross-Sectional
Studies; Female; Health Surveys; Human; Male; Middle Age;
Negroid Race; Risk; Sex Factors; United States
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0021-9681
- Country of Publication
- ENGLAND
Record 6 from database: MEDLINE
Return
To Top
- Title
- Heart rate variability in patients with diabetes
mellitus, ischemic heart disease, and congestive heart
failure.
- Author
- Takase B; Kurita A; Noritake M; Uehata A; Maruyama T;
Nagayoshi H; Nishioka T; Mizuno K; Nakamura H
- Address
- First Department of Internal Medicine, National Defense
Medical College, Saitama, Japan.
- Source
- J Electrocardiol, 1992 Apr, 25:2, 79-88
- Abstract
- The prognosis of patients with heart disease and
prediction of sudden cardiac death can be assessed through
heart rate variability, an indirect measure of abnormal
autonomic control. The authors have evaluated the heart
rate variability by 24-hour ambulatory
electrocardiographic monitoring in 25 diabetic patients,
19 ischemic heart disease patients, 18 congestive heart
failure patients, and 10 normal subjects. Thirteen
diabetic patients had autonomic neuropathy and 12 patients
did not. Heart rate variability index (mean SD) in
patients with diabetes mellitus, ischemic heart disease,
and congestive heart failure was significantly lower (34.5
+/- 12.6 ms, 43.7 +/- 15.4 ms, and 34.6 +/- 15.8 ms vs
65.6 +/- 16.7 ms, p less than 0.05) than that of normal
subjects. Mean SD was significantly lower in patients with
autonomic neuropathy as compared to patients without
autonomic neuropathy (26.4 +/- 6.5 ms vs 44.2 +/- 11.0 ms,
p less than 0.05) mean SD as compared to survivors: 49 +/-
7 ms in patients with mild ischemic heart disease, 48 +/-
15 ms in patients with severe ischemic heart disease, and
23 +/- 7 ms in patients who died. Similarly, the mean SD
in 4 congestive heart failure patients who died was lower
significantly (p less than 0.05) than in those who
survived (19.0 +/- 5.6 ms vs 40.0 +/- 14.5 ms). Among
congestive heart failure patients, clinical improvement by
therapy was associated with a significant increase in mean
SD. When the mean SD of 30 ms was used as the cutoff point
for detection of autonomic dysfunction or patient death,
specificity exceeded 90% and sensitivity was 75%.(ABSTRACT
TRUNCATED AT 250 WORDS)
- Language of Publication
- English
- Unique Identifier
- 92395400
Return
To Top
- MeSH Heading (Major)
- Coronary Disease|EP/*PP; Diabetes Mellitus, Non-Insulin-Dependent|EP/*PP;
Heart Failure, Congestive|EP/*PP; Heart Rate|*PH
- MeSH Heading
- Adult; Aged; Analysis of Variance; Circadian Rhythm|PH;
Comparative Study; Coronary Angiography; Diabetic
Neuropathies|EP/PP; Echocardiography; Electrocardiography,
Ambulatory|IS/MT/SN; Female; Human; Male; Middle Age
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0022-0736
- Country of Publication
- UNITED STATES
Record 7 from database: MEDLINE
Return
To Top
- Title
- Decreased heart rate variability in patients with
diabetes mellitus and ischemic heart disease.
- Author
- Fujimoto Y; Fukuki M; Hoshio A; Sasaki N; Hamada T;
Tanaka Y; Yoshida A; Shigemasa C; Mashiba H
- Address
- First Department of Internal Medicine, Tottori
University Hospital, Yonago, Japan.
- Source
- Jpn Circ J, 1996 Dec, 60:12, 925-32
- Abstract
- We investigated the characteristics of decreased heart
rate variability (HRV) in diabetic patients with ischemic
heart disease (IHD). Twenty-one healthy control subjects,
17 diabetic patients without IHD, and 33 diabetic patients
with IHD were studied. The diabetic patients with IHD were
subdivided into 2 groups according to the severity of
their IHD: severe or mild. HRV was evaluated in all
subjects using the spectral variables of the
all-frequency, low-frequency, high-frequency (AF, LF, HF)
components and the LF/HF ratio were determined from Holter
recordings. The AF and LF components in patients with
diabetes only or diabetes and severe IHD were
significantly lower than in control group, but the HF
component was significantly lower only in the group of
patients with diabetes and severe IHD. The LF/HF ratio did
not differ significantly among the 4 groups, but was the
lowest in diabetic patients without IHD. Patients with
diabetes and mild IHD showed a slight decrease in HRV, but
this was not significant. With regard to the circadian
rhythm of HRV, the AF and LF components in patients with
diabetes-only or diabetes and severe IHD were
significantly decreased and showed the same pattern
throughout the day. However, the HF component was
decreased during more time zones in patients with diabetes
and severe IHD, whereas the LF/HF ratio was lower during
more time zones in the diabetes-only group. All spectral
variables showed a tendency to be inversely related to the
duration of diabetes in all diabetic patients. In
particular, the LF/HF ratio showed a significant negative
correlation. The HRV of diabetic patients was
characterized by a decreased LF/HF ratio. It was concluded
that, although HRV in diabetic patients with severe IHD
was reduced mainly as a result of diabetic neuropathy,
this was also partly due to a decline in parasympathetic
tone as a result of myocardial injury.
- Language of Publication
- English
- Unique Identifier
- 97149888
Return
To Top
- MeSH Heading (Major)
- Diabetes Mellitus|CO/*PP; Heart Rate|*PH; Myocardial
Ischemia|CO/*PP
- MeSH Heading
- Aged; Circadian Rhythm|PH; Electrocardiography,
Ambulatory; Female; Human; Male; Middle Age; Prognosis;
Time Factors
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0047-1828
- Country of Publication
- JAPAN
Record 8 from database: MEDLINE
Return
To Top
- Title
- Determinants for coronary heart disease in
non-insulin-dependent diabetes mellitus: lessons from the
diabetes intervention study.
- Author
- Hanefeld M; Schmechel H; Julius U; Schwanebeck U
- Address
- Department of Clinical Metabolic Research, Medical
Faculty, Technical University Dresden, Germany.
- Source
- Diabetes Res Clin Pract, 1996 Feb, 30 Suppl:, 67-70
- Abstract
- In NIDDM a clustering of established coronary risk
factors, e.g. the metabolic syndrome is responsible for
excessive incidence of myocardial infarction. The harmful
effects of these risk factors are aggravated by poor
glucose control. Hyperinsulinaemia is associated with a
higher level of risk factors for coronary heart disease.
Individuals with subsequent myocardial infarction exhibit
higher levels of serum insulin at entry. However, insulin
in multivariate analysis was no independent risk factor.
Perfect control of blood glucose, triglycerides and blood
pressure was associated with a lower incidence of coronary
heart disease. By extrapolation an integrated approach to
correct the anomalies of the metabolic syndrome seems to
be necessary to prevent macroangiopathy and improve life
expectancy.
- Language of Publication
- English
- Unique Identifier
- 96252128
Return
To Top
- MeSH Heading (Major)
- Coronary Disease|*; Diabetes Mellitus,
Non-Insulin-Dependent|*PP
- MeSH Heading
- Clinical Trials; Human; Insulin|BL; Multicenter Studies;
Myocardial Infarction; Risk Factors
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0168-8227
- Country of Publication
- IRELAND
Record 9 from database: MEDLINE
Return
To Top
- Title
- Diabetes and coronary heart disease in American Indians:
The Strong Heart Study.
- Author
- Howard BV; Lee ET; Fabsitz RR; Robbins DC; Yeh JL; Cowan
LD; Welty TK
- Address
- Medlantic Research Institute, Washington, DC 20010, USA.
- Source
- Diabetes, 1996 Jul, 45 Suppl 3:, S6-13
- Abstract
- Coronary heart disease (CHD) is the leading cause of
death among American Indians. However, information on the
prevalence of CHD and its association with known risk
factors is limited. The purpose of the Strong Heart Study
is to quantify CHD and its risk factors among three
geographically diverse groups of American Indians. The
population consists of 4,549 adults between 45 and 74
years of age in 13 Indian communities in Arizona,
Oklahoma, and South and North Dakota. The phase I
examination (1989-1991) revealed very high prevalence
rates of diabetes that ranged from 33 to 72% in men and
women in the three centers. Prevalence rates of definite
myocardial infarction (MI) and definite CHD were higher in
men than in women in all three centers (P < 0.0001) and
in those with diabetes (P = 0.002 and P = 0.0003 in women
and men respectively). Diabetes was associated with a
relatively greater increase in prevalence of MI
(prevalence rate = 3.8 vs. 1.9) and CHD (prevalence rate =
4.6 vs. 1.8) in women than in men. Logistic regression
analysis indicated that the prevalence of CHD among
American Indians was significantly related to age,
diabetes, hypertension, albuminuria, percentage of body
fat, smoking, high concentrations of plasma insulin, and
low concentrations of HDL cholesterol. Lower prevalence
rates of CHD were found in Arizona despite higher rates of
diabetes, obesity, hypertension, and albuminuria; these
lower rates may be in part related to lower smoking
frequency and lower concentrations of total and LDL
cholesterol. These findings from the baseline Strong Heart
Study examination emphasize the relative importance of
diabetes and its associated variables as risk factors for
CHD among American Indian populations.
- Language of Publication
- English
- Unique Identifier
- 96289825
Return
To Top
- MeSH Heading (Major)
- Coronary Disease|*EP; Diabetes Mellitus|*EP
- MeSH Heading
- Adult; Aged; Female; Fibrinogen|AN; Human; Indians,
North American; Lipoproteins|BL; Male; Middle Age;
Obesity|CO; Odds Ratio; Regression Analysis; Risk Factors;
Smoking; Socioeconomic Factors; Tobacco
- Publication Type
- JOURNAL ARTICLE; MULTICENTER STUDY
- ISSN
- 0012-1797
- Country of Publication
- UNITED STATES
Record 10 from database: MEDLINE
Return
To Top
Back 10 records
- Title
- Diabetes and the heart: coronary heart disease.
- Author
- Jarrett J
- Address
-
- Source
- Clin Endocrinol Metab, 1977 Jul, 6:2, 389-402
- Abstract
- 1. Diabetics have a greater risk of experiencing and of
dying from a CHD event than age matched non-diabetics. 2.
The excess risk is particularly notable in insulin
dependent female diabetics who seem to lose the usual
'protection' accorded to women. 3. The cause or causes of
the excess risk are not known. There are a variety of
'risk factors' observed in diabetics which, in sum, may
contribute. 4. At least in insulin-dependent diabetics
some cardiac morbidity and mortality may also be due, not
to coronary heart disease, but to a cardiomyopathy
secondary to intramural obstructive vascular disease
and/or disordered myocardial metabolism. 5. No therapy has
yet been convincingly proved to reduce (or to increase)
the risk of cardiac morbidity or mortality. Nevertheless,
in treating diabetics there is an a priori case for using
diets designed to lower plasma lipid levels as well as the
blood sugar, for early treatment of hypertension and for
discouraging cigarette smoking.
- Language of Publication
- English
- Unique Identifier
- 77244722
Return
To Top
- MeSH Heading (Major)
- Coronary Disease|*/BL/CO/EP/MO; Diabetic Angiopathies|*/BL/CO/EP/MO
- MeSH Heading
- Adolescence; Adult; Age Factors; Cholesterol|BL; Female;
Human; Hypertension|CO/EP; Male; Middle Age; Obesity|CO;
Risk; Sex Factors; Smoking; Triglycerides|BL
- Publication Type
- JOURNAL ARTICLE; REVIEW
- ISSN
- 0300-595X
- Country of Publication
- ENGLAND
Record 11 from database: MEDLINE
Return
To Top
- Title
- Prevalence of coronary heart disease in subjects with
normal and impaired glucose tolerance and
non-insulin-dependent diabetes mellitus in a biethnic
Colorado population. The San Luis Valley Diabetes Study.
- Author
- Rewers M; Shetterly SM; Baxter J; Marshall JA; Hamman RF
- Address
- Department of Preventive Medicine and Biometrics,
University of Colorado School of Medicine, Denver.
- Source
- Am J Epidemiol, 1992 Jun, 135:12, 1321-30
- Abstract
- The prevalence of coronary heart disease was studied in
1984-1988 in 1,092 individuals with normal glucose
tolerance, 173 individuals with impaired glucose
tolerance, and 429 individuals with non-insulin-dependent
diabetes mellitus, who were age 25-74 years and were from
a biethnic community in the San Luis Valley, Colorado.
Glucose tolerance was classified using the World Health
Organization criteria, and coronary heart disease
prevalence was assessed using the Rose Questionnaire and a
resting electrocardiogram. Compared with normal glucose
tolerance, coronary heart disease was significantly more
prevalent in diabetic non-Hispanic white women (odds ratio
(OR) for all end points combined = 3.2, 95% confidence
interval (Cl) 1.8-5.5) and men (OR = 1.9, 95% Cl 1.1-3.3)
and in diabetic Hispanic women (OR = 1.7, 95% Cl 1.1-2.5),
but not men (OR = 1.0, 95% Cl 0.6-1.7). Among diabetic
men, the prevalence of possible myocardial infarction was
lower in Hispanics than in non-Hispanic whites (OR = 0.4,
95% Cl 0.2-0.7). Similar patterns of coronary heart
disease were observed in individuals with impaired glucose
tolerance. The paradoxically low prevalence of coronary
heart disease in Hispanics with non-insulin-dependent
diabetes mellitus, especially men, may be due to unknown
protective factors, increased case fatality, or competing
mortality in this group.
- Language of Publication
- English
- Unique Identifier
- 92377784
Return
To Top
- MeSH Heading (Major)
- Coronary Disease|CO/*EH; Diabetes Mellitus,
Non-Insulin-Dependent|*CO; Glucose Tolerance Test|*;
Hispanic Americans|*; Whites|*
- MeSH Heading
- Adult; Aged; Colorado|EP; Comparative Study;
Cross-Sectional Studies; Female; Human; Male; Middle Age;
Prevalence; Risk Factors; Support, U.S. Gov't, P.H.S.
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0002-9262
- Country of Publication
- UNITED STATES
Record 12 from database: MEDLINE
Return
To Top
- Title
- The level of autoantibodies against oxidized LDL is not
associated with the presence of coronary heart disease or
diabetic kidney disease in patients with
non-insulin-dependent diabetes mellitus.
- Author
- Leinonen JS; Rantalaiho V; Laippala P; Wirta O;
Pasternack A; Alho H; Jaakkola O; Ylä Herttuala S;
Koivula T; Lehtimäki T
- Address
- Medical School, University of Tampere, and Department of
Clinical Chemistry, Tampere University Hospital, Finland.
bljale@uta.fi
- Source
- Free
| |
