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Record 1
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- Title
- Prospective comparison of modified
fat-high-carbohydrate with standard
low-carbohydrate dietary advice in the
treatment of diabetes: one year
follow-up study.
- Author
- Hockaday TD; Hockaday JM; Mann JI;
Turner RC
- Address
-
- Source
- Br J Nutr, 1978 Mar, 39:2, 357-62
- Abstract
- 1. A prospective randomized study of
two dietary regimens has been started in
newly-diagnosed diabetics to determine
their effect on circulating metabolites
and on diabetic complications. 2. During
the first year of treatment the fasting
plasma glucose concentrations on both
the low-carbohydrate diet and the
high-carbohydrate, modified-fat (MF)
diet showed a similar decrease. 3.
Plasma cholesterol showed a sustained
decrease only in patients recommended a
MF diet. Transient changes in plasma
triglyceride concentrations occurred in
patients on both dietary regimens. 4.
Increased plasma cholesterol levels are
associated with atheromatous disease
which is common in diabetics in Europe
and North America. A MF diet may
therefore have an advantage in that it
lowers the plasma cholesterol as well as
being effective in lowering the plasma
glucose.
- Language of Publication
- English
- Unique Identifier
- 78124119
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- MeSH Heading (Major)
- Diabetes Mellitus|BL/*DH; Dietary
Carbohydrates|*AD
- MeSH Heading
- Adult; Aged; Blood Glucose|AN; Body
Weight; Cholesterol|BL; Dietary Fats|AD;
Human; Middle Age; Prospective Studies;
Time Factors; Triglycerides|BL
- Publication Type
- CLINICAL TRIAL; JOURNAL ARTICLE;
RANDOMIZED CONTROLLED TRIAL
- ISSN
- 0007-1145
- Country of Publication
- ENGLAND
Record 2
from database: MEDLINE
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- Title
- High carbohydrate-high fibre diets in
poorly controlled diabetes.
- Author
- Lousley SE; Jones DB; Slaughter P;
Carter RD; Jelfs R; Mann JI
- Address
-
- Source
- Diabet Med, 1984 May, 1:1, 21-5
- Abstract
- Fifteen non-insulin-dependent diabetic
patients with persistently elevated
blood glucoses despite high doses of
oral hypoglycaemic agents, were randomly
allocated to a high carbohydrate-high
fibre diet (HC) or a reinforced low
carbohydrate diet (LC). After six weeks
the diets were reversed for a similar
period. Immediately preceding the study
and at the end of each dietary period
24-h biochemical profiles were
performed. In the 11 patients who
completed the study, fasting and
preprandial glucose, percentage
glycosylated haemoglobin, VLDL
cholesterol and mean 24-h triglycerides
were significantly lower on HC than on
LC or during the initial profile on
their usual diet. There was no
significant difference in any of the
measurements on LC compared with the
usual diet. Previous studies of high
carbohydrate-high fibre diets in
diabetes have been carried out in
relatively well-controlled patients.
These data show that poorly controlled
non-insulin-dependent patients have an
even more striking response.
- Language of Publication
- English
- Unique Identifier
- 87274655
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- MeSH Heading (Major)
- Diabetes Mellitus, Non-Insulin-Dependent|BL/*DH/PP;
Dietary Carbohydrates|*AD; Dietary
Fiber|*AD
- MeSH Heading
- Aged; Blood Glucose|AN/ME;
Cholesterol|BL; Comparative Study;
Hemoglobin A, Glycosylated|AN; Human;
Lipoproteins, HDL Cholesterol|BL;
Lipoproteins, LDL Cholesterol|BL;
Lipoproteins, VLDL|BL; Middle Age;
Random Allocation; Support, Non-U.S.
Gov't; Triglycerides|BL
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0742-3071
- Country of Publication
- ENGLAND
Record 3 from database: MEDLINE
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- Title
- Lente carbohydrate: a newer approach
to the dietary management of diabetes.
- Author
- Jenkins DJ
- Address
-
- Source
- Diabetes Care, 1982 Nov, 5:6, 634-41
- Abstract
- The dietary fiber hypothesis has
stimulated interest in the possibility
that the glycemic response to
carbohydrate foods may be reduced by
modifying gastrointestinal events to
produce sustained-release or "lente"
carbohydrate. Associated with this
interest, a new branch of pharmacology
has been developed involving the use of
purified fiber preparations and enzyme
inhibitors. These measures, together
with the selection of diets containing
foods that naturally release their
carbohydrate products of digestion
slowly, may contribute a useful facet to
diabetic management in the future.
- Language of Publication
- English
- Unique Identifier
- 87132860
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- MeSH Heading (Major)
- Diabetes Mellitus,
Insulin-Dependent|*DH; Diabetes
Mellitus, Non-Insulin-Dependent|*DH;
Diabetic Diet|*; Dietary
Carbohydrates|*AD; Dietary Fiber|*AD
- MeSH Heading
- Galactans|AD; Human; Mannans|AD;
Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0149-5992
- Country of Publication
- UNITED STATES
Record 4 from database: MEDLINE
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- Title
- Decreased insulin requirement and
improved control of diabetes in pregnant
women given a high-carbohydrate,
high-fiber, low-fat diet.
- Author
- Ney D; Hollingsworth DR; Cousins L
- Address
-
- Source
- Diabetes Care, 1982 Sep, 5:5, 529-33
- Abstract
- Five quantitative measures of diabetic
control [HbA1c determinations, mean 24-h
plasma glucose values, mean amplitude of
glycemic excursions (MAGE), mean 24-h
urinary loss of glucose, and daily
exogenous insulin requirement] were
compared in 20 pregnant women who were
randomly assigned to either a
high-carbohydrate, high-fiber diet (HCF)
that was low in fat or to a control diet
commonly prescribed for pregnancy.
Eleven women followed the HCF diet and
nine subjects, the control diet, from
baseline entry into the study until
delivery. Dietary compliance was
excellent, with 78% of the women in each
group rated good or acceptable. HbA1c
values were similar in both groups at
baseline (HCF: 11.0 +/- 0.5% versus
control: 10.2 +/- 0.6%), with no
different predelivery values (8.6 +/-
0.4%). Mean 24-h plasma glucose levels
improved in patients on both diets, with
lower values noted in the HCF group at
predelivery. MAGE values and standard
deviations did not differ significantly
in the two groups. Glycosuria decreased
markedly in both dietary groups, but
differences between groups were not
significant. Improved control of
diabetes on the HCF diet was achieved
with significantly lower increments in
insulin dose during gestation (HCF
baseline: 32 +/- 8 U/24 h to 66 +/- 10
U/24 h versus control baseline: 27 +/- 9
U/24 h to 108 +/- 12 U/24 h, P less than
0.03). Outcome of pregnancy did not
differ in the two groups of patients,
but women on the HCF diet gained less
weight than those on the control diet
(26 +/- 3 lb versus 35 +/- 5 lb, P less
than 0.05). Mean newborn gestational age
was similar in the two groups (HCF: 37.2
+/- 0.7 wk versus control: 36.5 +/- 0.7
wk). Mean birth weight in infants of HCF
mothers was 3809 +/- 248 g versus 3313
+/- 278 g in infants of control mothers
(P less than 0.05). We conclude that
although marked improvement of diabetic
control occurred on both regimens,
patients on the HCF diet achieved better
control of diabetes with significantly
lower increments in exogenous insulin.
- Language of Publication
- English
- Unique Identifier
- 84235309
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- MeSH Heading (Major)
- Insulin|*AD; Pregnancy in Diabetes|*DH
- MeSH Heading
- Adult; Blood Glucose|AN; Comparative
Study; Dietary Carbohydrates|AD; Dietary
Fats|AD; Dietary Fiber|AD; Female;
Human; Pregnancy; Support, U.S. Gov't,
P.H.S.
- Publication Type
- CLINICAL TRIAL; JOURNAL ARTICLE;
RANDOMIZED CONTROLLED TRIAL
- ISSN
- 0149-5992
- Country of Publication
- UNITED STATES
Record 5 from database: MEDLINE
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- Title
- Separate influence of dietary
carbohydrate and fibre on the metabolic
control in diabetes.
- Author
- Riccardi G; Rivellese A; Pacioni D;
Genovese S; Mastranzo P; Mancini M
- Address
-
- Source
- Diabetologia, 1984 Feb, 26:2, 116-21
- Abstract
- To clarify the separate influences of
digestible carbohydrate and of dietary
fibre on blood glucose control and serum
lipoproteins, 14 diabetic patients (six
Type 1 and eight Type 2) were submitted
to three weight-maintaining diets for 10
days each: (1) low carbohydrate/low
fibre diet with 42% carbohydrate and 20
g fibre; (2) high carbohydrate/low fibre
diet (carbohydrate 53%, fibre 16 g); (3)
high carbohydrate/ high fibre diet
(carbohydrate 53%, fibre 54 g). In
comparison with the low carbohydrate/low
fibre diet, the 2-h post-prandial blood
glucose and the daily blood glucose
profile decreased significantly on the
high carbohydrate/high fibre diet,
without significant changes during the
high carbohydrate/low fibre diet. The
diet-induced modifications of blood
glucose control were similar in both
types of diabetic patients (two-way
analysis of variance: F = 5.86, p less
than 0.02 for dietary treatment and F =
2.09, NS for type of diabetes). Total
and low-density lipoprotein cholesterol
were also decreased after the high
carbohydrate/high fibre diet in
comparison with the low carbohydrate/low
fibre diet (p less than 0.001 for both),
while they were not significantly
modified after the high carbohydrate/low
fibre diet. Again the modifications of
low density lipoprotein cholesterol
induced by diet were similar in both
types of diabetic patients (F = 10.02, p
less than 0.005 for dietary treatment
and F = 0.14 for type of diabetes, NS).
High-density lipoprotein cholesterol was
lower after the two test diets than
after the low carbohydrate/low fibre
diet.(ABSTRACT TRUNCATED AT 250 WORDS)
- Language of Publication
- English
- Unique Identifier
- 84183357
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full text for this document
- MeSH Heading (Major)
- Diabetes Mellitus, Insulin-Dependent|BL/DH/*ME;
Diabetes Mellitus, Non-Insulin-Dependent|BL/DH/*ME;
Dietary Carbohydrates|*AD; Dietary
Fiber|*AD
- MeSH Heading
- Adult; Blood Glucose|ME; Body Weight;
Cholesterol|BL; Comparative Study;
Diabetic Diet; Human; Lipoproteins,
HDL|BL; Lipoproteins, LDL|BL;
Lipoproteins, VLDL|BL; Middle Age;
Support, Non-U.S. Gov't
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0012-186X
- Country of Publication
- GERMANY, WEST
Record 6 from database: MEDLINE
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- Title
- High-carbohydrate, high-fiber diet in
children with type I diabetes mellitus.
- Author
- Lindsay AN; Hardy S; Jarrett L;
Rallison ML
- Address
-
- Source
- Diabetes Care, 1984 Jan, 7:1, 63-7
- Abstract
- The effects of a high-carbohydrate,
high-fiber (HCHF) diet on glucose
control was evaluated in 12 children
with type I diabetes mellitus. The
children had had diabetes for an average
of 5.25 yr; their mean glycosylated
hemoglobin was 12.4% (normal 5-9%), and
C-peptide was virtually undetectable in
all but one. They were followed on a
regular diabetic diet for 10 days at
home and in the hospital and then were
studied on a HCHF diet for 14 days. The
HCHF diet contained 60% carbohydrate and
30 g of fiber per 1000 cal provided
through grains, fruits, vegetables, and
high-fiber crackers. Capillary blood
glucose levels were monitored at home
before meals and at bedtime, and venous
plasma glucose levels were measured in
the hospital before and after each meal
and during the night. Plasma glucose was
measured serially after test meals with
each diet. There was no significant
difference in blood glucose levels
preprandially, postprandially, and while
fasting on the two diets. The 24-h
glucose profiles and posttest meal
profiles obtained during both diets were
remarkably similar. We conclude that a
diet high in fiber and carbohydrate has
limited application in children with
type I diabetes mellitus who have no
residual beta-cell function.
- Language of Publication
- English
- Unique Identifier
- 84158086
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- MeSH Heading (Major)
- Diabetes Mellitus, Insulin-Dependent|BL/*DH;
Dietary Carbohydrates|*AD; Dietary
Fiber|*AD
- MeSH Heading
- Adolescence; Blood Glucose|AN; Child;
Hemoglobin A, Glycosylated|AN; Human;
Support, U.S. Gov't, P.H.S.; Time
Factors
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0149-5992
- Country of Publication
- UNITED STATES
Record 7 from database: MEDLINE
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- Title
- Rationale for changes in the dietary
management of diabetes. Fat,
carbohydrate, and fiber.
- Author
- El Beheri Burgess BR
- Address
-
- Source
- J Am Diet Assoc, 1982 Sep, 81:3,
258-61
- Abstract
- Roughly three-quarters of Americans
with diabetes die from atherosclerosis.
Although the pathogenesis of
cardiovascular disease in diabetes is
not completely understood, diabetes is
frequently associated with
hyperlipidemia, often considered a major
determinant of atherosclerosis, and with
hyperglycemia, which may function as an
independent risk factor. The new higher
carbohydrate diets for management of
diabetes facilitate reduction in the
proportion of fat kilocalories. When
total kilocalories are controlled,
improvement in glucose tolerance also
occurs in individuals with diabetes who
have available endogenous or exogenous
insulin. It has recently been
demonstrated in subjects with diabetes
that a mixture of carbohydrate and fiber
and a high, rather than low, level of
carbohydrate facilitate glycemic
control. Inclusion of fiber-rich foods
in meal plans for patients with diabetes
augments established modes of therapy,
which focus on weight control for Type
II diabetes while synchronizing food
intake and insulin for Type I diabetes.
- Language of Publication
- English
- Unique Identifier
- 82266712
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- MeSH Heading (Major)
- Diabetes Mellitus|CO/*DH; Diabetic
Diet|*TD
- MeSH Heading
- Atherosclerosis|ET/PC; Cardiovascular
Diseases|ET; Dietary Carbohydrates|ME;
Dietary Fats|ME; Dietary Fiber|ME;
Female; Human; Male
- Publication Type
- JOURNAL ARTICLE
- ISSN
- 0002-8223
- Country of Publication
- UNITED STATES
Record 8 from database: MEDLINE
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- Title
- The effects of energy and carbohydrate
restriction in patients with chronic
diabetes mellitus.
- Author
- Perkins JR; West TE; Sönksen PH; Lowy
C; Iles C
- Address
-
- Source
- Diabetologia, 1977 Dec, 13:6, 607-14
- Abstract
- Thirty-five freshly presenting,
diabetic patients received 5 hour, 100 g
oral glucose tolerance tests when first
seen and after a period of carbohydrate
and energy restriction. After treatment,
the significant improvement in glucose
tolerance was accompanied by increased
insulin secretion and lower
concentrations of blood ketone bodies,
lactate, glycerol, FFA, triglycerides,
cholesterol and pre-beta lipoprotein.
There were no significant changes in
serum growth hormone or blood pyruvate
concentrations. Improvement in glucose
tolerance was greater in patients who
were obese (greater than 115% of
desirable body weight for height) on
presentation and was related to the
improvement in insulin secretion and the
diminished lipolysis. An hypothesis to
explain the changes in insulin secretion
is prosposed. Eleven out of the 35
patient
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