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Two Scientific Studies On Phosphoric Acid And Soft Drinks

       
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Results for your query on December 24, 2000:
Search all fields for: phosphoric acid And soft drink
Published in 1966 through 1999
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Shuster J, et al; Soft drink consumption and urinary stone recurrence: a randomized prevention trial. (J Clin Epidemiol, 1992 Aug, Abstract available) [MEDLINE]

2 Fernando GR, et al; Consumption of soft drinks with phosphoric acid as a risk factor for the development of hypocalcemia in postmenopausal women. (J Clin Epidemiol, 1999 Oct, Abstract available) [MEDLINE]

       

Record 1 from database: MEDLINE
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Title
Soft drink consumption and urinary stone recurrence: a randomized prevention trial.
Author
Shuster J; Jenkins A; Logan C; Barnett T; Riehle R; Zackson D; Wolfe H; Dale R; Daley M; Malik I; et al
Address
Research Assistance Corp, Gainesville, FL 32605.
Source
J Clin Epidemiol, 1992 Aug, 45:8, 911-6
Abstract
The object of this study was to determine if a strong association between soft drink (soda) consumption and recurrence of urinary stone disease, found in an earlier case-control study of adult males, had a causal component. The study sample consisted of 1009 male subjects, who completed an episode of urinary stone disease, who were aged 18-75 at that time, and who reported consuming at least 160 ml per day of soft drinks. Half of the subjects were randomized to refrain from consuming soft drinks, while the remaining subjects served as controls. The intervention group had an observed 6.4% advantage in actuarial 3 yr freedom from recurrence (p = 0.023 one-sided) over the control group. One important secondary finding was that for those who reported at the time of the index stone that their most consumed drink was acidified by phosphoric acid but not citric acid, the experimental group had a 15% higher 3 yr recurrence-free rate than the controls, p = 0.002, while for those who reported at the time of the index stone that their most consumed drink was acidified by citric acid with or without phosphoric acid, the experimental group had a similar 3 yr recurrence-free rate to the controls, p = 0.55. This interaction was significant, p = 0.019.
Language of Publication
English
Unique Identifier
92325739

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MeSH Heading (Major)
Beverages|*AE; Urinary Calculi|*ET
MeSH Heading
Actuarial Analysis; Adolescence; Adult; Aged; Citrates|AE; Human; Male; Middle Age; Patient Compliance; Phosphoric Acids|AE; Recurrence; Support, Non-U.S. Gov't; Support, U.S. Gov't, P.H.S.

Publication Type
CLINICAL TRIAL; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
ISSN
0895-4356
Country of Publication
ENGLAND

Record 2 from database: MEDLINE
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Title
Consumption of soft drinks with phosphoric acid as a risk factor for the development of hypocalcemia in postmenopausal women.
Author
Fernando GR; Martha RM; Evangelina R
Address
Mexican Social Security Institute, Durango. guerrero@omanet.com.mx
Source
J Clin Epidemiol, 1999 Oct, 52:10, 1007-10
Abstract
The objective of this study was to determine the relationship between the consumption of phosphoric acid-containing soft drinks and hypocalcemia in postmenopausal women. A case control study was designed to include 21 cases and 64 controls, matched by age and menopausal duration with similar family income, scholarship, and daily dietary intakes. Clinical and dietetic conditions that may produce hypocalcemia were considered as exclusion criteria. Cases were defined as a serum Ca level < or = 8.8 mg/dl, and controls as a serum CA level > 8.8 mg/dl. 
 
Women in the case group had a higher consumption of phosphoric acid-containing soft drink, and showed increased serum levels of PTH and hyperphosphaturia, than those in the control group without significant differences in 1,25(OH)2D3. 
 
In the multivariate regression analysis consumption of one or more bottles per day of cola soft drinks showed association with hypocalcemia (1.28, CI 95% 1.06-1.53).
 
The consumption of soft drinks with phosphoric acid should be considered as an independent risk factor for hypocalcemia in postmenopausal women.
 
Language of Publication
English
Unique Identifier
99441922

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MeSH Heading (Major)
Carbonated Beverages|*AE; Hypocalcemia|*ET; Phosphoric Acids|*AE; Postmenopause|*
MeSH Heading
Case-Control Studies; Chi-Square Distribution; Female; Human; Middle Age; Regression Analysis; Risk Factors; Statistics, Nonparametric

Publication Type
JOURNAL ARTICLE
ISSN
0895-4356
Country of Publication
ENGLAND

 

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