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	2. Prevention of Metastasis     It has long been held by cancer researchers that cancer can be cured if the primary lesion is eliminated. This is not as simple as it sounds, however, as cancer cells mix in the bloodstream and metastasize or migrate throughout the body. Doctors working with the germanium compound have repeatedly confirmed,  however, that patients receiving the compound have shown virtually no metastasis. This alone is tremendous news in cancer treatment since, if metastasis can be prevented, cancer can be stopped with a massive attack on the primary lesion.     Although it is known that the dehydrogenating action of the compound has an inhibitory effect on the growth of cancer cells and plays an important role in halting metastasis, precise details of its mechanism are not yet known. One important clue, however, is provided by Dr. Haruo Sato of Tohoku University (Japan), an authority on the metastasis of cancer. In a paper which he presented to the Japan Society for Cancer Therapy, he relates that cancer cells that have entered the bloodstream continue to move with the blood flow.  If a pathological condition should develop in a blood vessel, they will adhere to the wall of the vessel, eventually infiltrating and destroying it to proliferate outside. Secondary tumors can be prevented if action is taken to prevent the cells from adhering to the vessel.     Based on Dr. Haruo Sato's theory. a plausible explanation of how the organic germanium compound functions to prevent metastasis is that the increase in the body's supply of oxygen brought about by the compound sharply reduces blood viscosity, thereby improving the blood flow. From a hydrodynamic point of view, cancer cells as an alien substance will continue to flow with the blood without being pushed aside until they reach the capillaries, where they are oxidized and destroyed by the dehydrogenating action of the compound. This explanation is hypothetical and is still being tested, but is not improbable in the light of the activity of the germanium compound.     Information gleaned from our laboratory experiments and clinical observations lend heavy support to the theory that cancer develops due to cellular oxygen deficiencies. Indication is that the high efficacy of the compound in treating lung cancer and liver cancer may be attributed to the activity of the germanium compound in the entire bloodstream flowing through these areas.     In one experiment, a group of five mice were given a hypodermic injection of cancer cells after administering a water solution of the organic germanium compound. Another group of five mice were given a hypodermic injection of cancer cells without administering the solution as a control. The hypodermic injection of cancer cells is a method of inducing cancer in mice generally practiced in the Cancer Research Institute.     The mice injected invariably developed cancer, except those five mice to which the germanium compound was also administered who failed to develop cancer.  This experiment was repeated twice, with the same result.

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