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Write To Karl Loren Table Of Contents

66 Studies:  Toxic Metals Found In Urine

by Karl Loren

Ultrasound & Heart Disease

 

Results for your query on July 30, 2000
Words in abstract only: heavy metal And urine
Published in 1966 through 1999
Only select references with abstracts available
Show references published in English only
Show references pertaining to humans

Documents: 1 to 66 of 66

1

Top

Melgaard B, et al; Heavy metal levels and delta-amino-levulinic acid dehydrase levels in peripheral polyneuropathy. (Acta Neurol Scand, 1976 Apr, Abstract available) [MEDLINE]

2 Morse DL, et al; Arsenic exposure in multiple environmental media in children near a smelter. (Clin Toxicol, 1979 Apr, Abstract available) [MEDLINE]
3 Kabzinski AK; Application of covalent affinity chromatography with thiol-disulphide interchange for determination of environmental exposition to heavy metals based on the quantitative determination of Zn-thionein from physiological human fluids by indirect method based on analysis of metal contents. (Biomed Chromatogr, 1998 Sep, Abstract available) [MEDLINE]
4 Boscolo P, et al; Urinary kallikrein activity of workers exposed to lead. (Br J Ind Med, 1978 Aug, Abstract available) [MEDLINE]
5 Wilde C; Aerosol metallic paints: deliberate inhalation. A study of inhalation and or ingestion of copper and zinc particles. (Int J Addict, 1975, Abstract available) [MEDLINE]
6 Hughes GS Jr, et al; Variegate porphyria and heavy metal poisoning from ingestion of "moonshine". (South Med J, 1983 Aug, Abstract available) [MEDLINE]
7 Iesato K, et al; Renal tubular dysfunction in Minamata disease. Detection of renal tubular antigen and beta-2-microglobin in the urine. (Ann Intern Med, 1977 Jun, Abstract available) [MEDLINE]
8 Lener J, et al; Effects of molybdenum on the organism (a review). (J Hyg Epidemiol Microbiol Immunol, 1984, Abstract available) [MEDLINE]
9 Rivlin RS; Misuse of hair analysis for nutritional assessment. (Am J Med, 1983 Sep, Abstract available) [MEDLINE]
10

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Lie A, et al; Mercury in urine.--Sex, age and geographic differences in a reference population. (Scand J Work Environ Health, 1982 Jun, Abstract available) [MEDLINE]

11 Sharma RP, et al; Analysis of submicrogramme levels of cadmium in whole blood, urine and hair by graphite furnace atomic absorption spectroscopy. (J Anal Toxicol, 1982 May, Abstract available) [MEDLINE]
12 Ahlskog JE, et al; Guamanian neurodegenerative disease: investigation of the calcium metabolism/heavy metal hypothesis. (Neurology, 1995 Jul, Abstract available) [MEDLINE]
13 Lombardo JV, et al; Tubulointerstitial diseases. (Am Fam Physician, 1980 Jan, Abstract available) [MEDLINE]
14 Buchet JP, et al; Assessment of renal function of workers exposed to inorganic lead, calcium or mercury vapor. (J Occup Med, 1980 Nov, Abstract available) [MEDLINE]
15 Hansen JC; The human health programme under AMAP. AMAP Human Health Group. Arctic Monitoring and Assessment Program. (Int J Circumpolar Health, 1998 Oct, Abstract available) [MEDLINE]
16 Ptashekas J, et al; Environmental and health monitoring in Lithuanian cities: exposure to heavy metals and benz(a)pyrene in Vilnius and Siauliai residents. (J Environ Pathol Toxicol Oncol, 1996, Abstract available) [MEDLINE]
17 Schäfer T, et al; Indoor risk factors for atopic eczema in school children from East Germany. (Environ Res, 1999 Aug, Abstract available) [MEDLINE]
18 Accomando J, et al; An unusual manifestation of diabetes mellitus. (Hosp Pract (Off Ed), 1999 May, Abstract available) [MEDLINE]
19 Zhang ZW, et al; Non-occupational lead and cadmium exposure of adult women in Bangkok, Thailand. (Sci Total Environ, 1999 Feb, Abstract available) [MEDLINE]
20

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Pierini G, et al; Atomic absorption spectrophotometry (AAS) for the evaluation of metallosis in prostheses and artificial organs: a new approach. (Int J Artif Organs, 1999 Jul, Abstract available) [MEDLINE]

21 Sata F, et al; Behavior of heavy metals in human urine and blood following calcium disodium ethylenediamine tetraacetate injection: observations in metal workers. (J Toxicol Environ Health, 1998 Jun, Abstract available) [MEDLINE]
22 Karpas Z, et al; Uranium in urine--normalization to creatinine. (Health Phys, 1998 Jan, Abstract available) [MEDLINE]
23 Mitane Y, et al; The role of metallothionein in the elevated excretion of copper in urine from people living in a cadmium-polluted area. (Fundam Appl Toxicol, 1986 Feb, Abstract available) [MEDLINE]
24 Kabzinski AK, et al; The application of affinity chromatography for quantitative determination of metallothionein in physiological fluids by an indirect method based on analysis of metal contents. (Biomed Chromatogr, 1995 May, Abstract available) [MEDLINE]
25 Omura Y, et al; Role of mercury (Hg) in resistant infections & effective treatment of Chlamydia trachomatis and Herpes family viral infections (and potential treatment for cancer) by removing localized Hg deposits with Chinese parsley and delivering effective antibiotics using various drug uptake enhancement methods. (Acupunct Electrother Res, 1995 Aug, Abstract available) [MEDLINE]
26 Kallio A, et al; Results of biomonitoring analyses in Biomonitoring Laboratory, Helsinki, Finland in 1997. (Toxicol Lett, 1999 Sep, Abstract available) [MEDLINE]
27 Ikeda M, et al; Urinary alpha1-microglobulin, beta2-microglobulin, and retinol-binding protein levels in general populations in Japan with references to cadmium in urine, blood, and 24-hour food duplicates. (Environ Res, 1995 Jul, Abstract available) [MEDLINE]
28 Huang WS, et al; Hepatocellular carcinoma presenting with acquired porphyria: a case report and review of the literature. (Chang Keng I Hsueh Tsa Chih, 1999 Mar, Abstract available) [MEDLINE]
29 Barceloux DG; Vanadium. (J Toxicol Clin Toxicol, 1999, Abstract available) [MEDLINE]
30

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Taylor SA, et al; The assessment of biomarkers to detect nephrotoxicity using an integrated database. (Environ Res, 1997 Oct, Abstract available) [MEDLINE]

31 Araki S, et al; Adjustment for urinary flow rate: an improved approach to biological monitoring. (Int Arch Occup Environ Health, 1990, Abstract available) [MEDLINE]
32 Maiorino RM, et al; Determination and metabolism of dithiol chelating agents. VI. Isolation and identification of the mixed disulfides of meso-2,3-dimercaptosuccinic acid with L-cysteine in human urine. (Toxicol Appl Pharmacol, 1989 Feb, Abstract available) [MEDLINE]
33 Bernard AM, et al; Assessment of urinary retinol-binding protein as an index of proximal tubular injury. (Clin Chem, 1987 Jun, Abstract available) [MEDLINE]
34 Lauwerys R, et al; Health risks associated with cobalt exposure--an overview. (Sci Total Environ, 1994 Jun, Abstract available) [MEDLINE]
35 Rezuke WN, et al; Arsenic intoxication presenting as a myelodysplastic syndrome: a case report. (Am J Hematol, 1991 Apr, Abstract available) [MEDLINE]
36 Ewers U, et al; Environmental exposure to cadmium and renal function of elderly women living in cadmium-polluted areas of the Federal Republic of Germany. (Int Arch Occup Environ Health, 1985, Abstract available) [MEDLINE]
37 Baser ME, et al; A statewide case registry for surveillance of occupational heavy metals absorption [see comments] (Am J Public Health, 1990 Feb, Abstract available) [MEDLINE]
38 Roels H, et al; Markers of early renal changes induced by industrial pollutants. III. Application to workers exposed to cadmium. (Br J Ind Med, 1993 Jan, Abstract available) [MEDLINE]
39 Villareal DT, et al; Painful diffuse osteosclerosis after intravenous drug abuse [see comments] (Am J Med, 1992 Oct, Abstract available) [MEDLINE]
40

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Hjorts‡ E, et al; Does N-acetylcysteine increase the excretion of trace metals (calcium, magnesium, iron, zinc and copper) when given orally? (Eur J Clin Pharmacol, 1990, Abstract available) [MEDLINE]

41 Roels H, et al; Markers of early renal changes induced by industrial pollutants. III. Application to workers exposed to cadmium. (Br J Ind Med, 1993 Jan, Abstract available) [MEDLINE]
42 Tolkoff Rubin NE, et al; Noninvasive renal diagnostic studies. (Clin Lab Med, 1988 Sep, Abstract available) [MEDLINE]
43 Díaz Barriga F, et al; Biological monitoring of workers at a recently opened hazardous waste disposal site. (J Expo Anal Environ Epidemiol, 1993, Abstract available) [MEDLINE]
44 Price RG, et al; Development and validation of new screening tests for nephrotoxic effects. (Hum Exp Toxicol, 1996 Mar, Abstract available) [MEDLINE]
45 Mulkey JP, et al; A review of thallium toxicity [published erratum appears in Vet Hum Toxicol 1993 Dec;35(6):511] (Vet Hum Toxicol, 1993 Oct, Abstract available) [MEDLINE]
46 Tsuda M, et al; Urinary concentrations of heavy metals in healthy Japanese under 20 years of age: a comparison between concentrations expressed in terms of creatinine and of selenium. (Tokai J Exp Clin Med, 1995 May, Abstract available) [MEDLINE]
47 Wolff C, et al; Deficiency of porphobilinogen synthase associated with acute crisis. Diagnosis of the first two cases in Chile by laboratory methods. (Eur J Clin Chem Clin Biochem, 1991 May, Abstract available) [MEDLINE]
48 Stennard FA, et al; Effect of prior, low-level cadmium exposure in vivo on metallothionein expression in cultured lymphocytes. (J Appl Toxicol, 1995 Jan, Abstract available) [MEDLINE]
49 Aposhian HV, et al; Mobilization of heavy metals by newer, therapeutically useful chelating agents. (Toxicology, 1995 Mar, Abstract available) [MEDLINE]
50

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Vacca CV, et al; The proteinuria of industrial lead intoxication. (Environ Res, 1986 Dec, Abstract available) [MEDLINE]

51 Griffin RM; Biological monitoring for heavy metals: practical concerns. (J Occup Med, 1986 Aug, Abstract available) [MEDLINE]
52 Mulkey JP, et al; A review of thallium toxicity [published erratum appears in Vet Hum Toxicol 1993 Dec;35(6):511] (Vet Hum Toxicol, 1993 Oct, Abstract available) [MEDLINE]
53 Bernard A, et al; Epidemiological application of early markers of nephrotoxicity. (Toxicol Lett, 1989 Mar, Abstract available) [MEDLINE]
54 Sanz Alaejos M, et al; Urinary selenium concentrations. (Clin Chem, 1993 Oct, Abstract available) [MEDLINE]
55 Maiorino RM, et al; Determination and metabolism of dithiol chelating agents. XVII. In humans, sodium 2,3-dimercapto-1-propanesulfonate is bound to plasma albumin via mixed disulfide formation and is found in the urine as cyclic polymeric disulfides. (J Pharmacol Exp Ther, 1996 Apr, Abstract available) [MEDLINE]
56 López Artíguez M, et al; Preconcentration of heavy metals in urine and quantification by inductively coupled plasma atomic emission spectrometry. (J Anal Toxicol, 1993 Jan, Abstract available) [MEDLINE]
57 Ganley CJ, et al; Increased renal tubular cell excretion by patients receiving chronic therapy with gold and with nonsteroidal anti-inflammatory drugs. (Clin Pharmacol Ther, 1989 Jul, Abstract available) [MEDLINE]
58 Asiedu P, et al; Metabolism of meso-2,3-dimercaptosuccinic acid in lead-poisoned children and normal adults. (Environ Health Perspect, 1995 Jul, Abstract available) [MEDLINE]
59 Paoletti P; Application of biomarkers in population studies for respiratory non-malignant diseases. (Toxicology, 1995 Jul, Abstract available) [MEDLINE]
60

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Claeys F, et al; Analytical quality control of cadmium and lead in blood and cadmium in urine: results of its implementation during a five-year epidemiological study. (IARC Sci Publ, 1992, Abstract available) [MEDLINE]

61 Gruener N; Early detection of changes in kidney function in workers exposed to solvents and heavy metals. (Isr J Med Sci, 1992 Aug, Abstract available) [MEDLINE]
62 Koizumi A, et al; Mercury, not sulphur dioxide, poisoning as cause of smelter disease in industrial plants producing sulphuric acid. (Lancet, 1994 Jun, Abstract available) [MEDLINE]
63 Haddy TB, et al; Minerals in hair, serum, and urine of healthy and anemic black children. (Public Health Rep, 1991 Sep, Abstract available) [MEDLINE]
64 Sanz Alaejos M, et al; Urinary selenium concentrations. (Clin Chem, 1993 Oct, Abstract available) [MEDLINE]
65 Borowiak K, et al; Chronic cadmium intoxication caused by a dental prosthesis. (Z Rechtsmed, 1990, Abstract available) [MEDLINE]
66 López Artíguez M, et al; Preconcentration of heavy metals in urine and quantification by inductively coupled plasma atomic emission spectrometry. (J Anal Toxicol, 1993 Jan, Abstract available) [MEDLINE]


       

Record 1 from database: MEDLINE
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Title
Heavy metal levels and delta-amino-levulinic acid dehydrase levels in peripheral polyneuropathy.
Author
Melgaard B; Clausen J; Rastogi SC
Address
 
Source
Acta Neurol Scand, 1976 Apr, 53:4, 291-307
Abstract
On the basis of assay of heavy metals in whole blood (lead, cadimum, chromium, copper, nickel and manganese) and delta-amino-levulinic-acid dehydrase (ALA-D) and ALA in urine in a normal Danish population, the levels of these clinco-chemical factors were assayed in 23 patients with peripheral neuropathy of unknown etiology. All patients studied showed electro-physiological sign of denervation and/or reduced motor or sensoric nerve conduction velocity. Cadmium and manganese were never found to be increased. In all but four patients, an increase of one or more heavy metals was found. Ten patients showed raised levels of two or more metals, the dominant metal being lead (10 cases), nine patients showed increased in chromium. A significant corrleation was found between increasing lead levels and decreasing ALA-D activity. Although normal concentrations of manganese were found, correlation analysis revealed a significant correlation between increased manganese and decreased ALA-D. The raised values of heavy metals could not be traced to occupational or other exposure to heavy metals and the increased values were not related to tobacco consumption. The findings are discussed in relation to known data on neuropathy and the results seem to indicate a multifactorial patholgenesis of the disease. Among factors contributing to the precipitation of the syndrome may be raised levels of heavy metals.
Language of Publication
English
Unique Identifier
76181095

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MeSH Heading (Major)
Hydro-Lyases|*BL; Metals|*BL; Peripheral Nervous System Diseases|*BL/EN; Porphobilinogen Synthase|*BL
MeSH Heading
Adult; Aged; Aminolevulinic Acid|UR; Cadmium|BL; Chromium|BL; Copper|BL; Female; Human; Lead|BL; Male; Manganese|BL; Middle Age; Nickel|BL

Publication Type
JOURNAL ARTICLE
ISSN
0001-6314
Country of Publication
DENMARK

Record 2 from database: MEDLINE
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Title
Arsenic exposure in multiple environmental media in children near a smelter.
Author
Morse DL; Harrington JM; Housworth J; Landrigan PJ; Kelter A
Address
 
Source
Clin Toxicol, 1979 Apr, 14:4, 389-99
Abstract
A nationwide survey of heavy-metal exposure in children living near primary nonferrous metal smelters demonstrated high urine arsenic levels in children living near a copper smelter in Ajo, Arizona. Airborne smelter emissions and drinking water were the apparent sources of exposure. To determine whether increased arsenic absorption had produced adverse health effects, we conducted an evaluation of 132 Ajo children 5 to 18 years old and compared results with those of 47 children from a comparison town with low arsenic exposure. Environmental testing showed that Ajo's municipal water supply contained arsenic in concentrations of 0.09 mg/l (the EPA standard is 0.05 mg/l); arsenic concentrations in dust averaged 342.2 microgram/g. Urine arsenic levels in Ajo children correlated positively with amount of tap-water consumed (r = .32, p less than. 0002) and with distance of residence from the smelter (r = .20, p less than .02). Tap-water drinkers had significantly higher urine arsenic levels than bottled water drinkers (t = 4.21 p less than .001). Mean urine arsenic levels were significantly higher for children in Ajo (4.75 microgram/100 ml) than for children in the comparison town (1.17 microgram/100 ml). Hair arsenic levels correlated poorly with arsenic exposure. Despite the study population's chronic exposure to elevated environmental levels of arsenic, no clinical or hematologic abnormalities attributable to arsenic were found.
Language of Publication
English
Unique Identifier
79235335

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MeSH Heading (Major)
Arsenic|*AN/PO/UR; Metallurgy|*
MeSH Heading
Adolescence; Arizona; Body Burden; Child; Child, Preschool; Copper; Dust|AN; Environmental Exposure; Hair|AN; Human; Support, U.S. Gov't, Non-P.H.S.; Water Supply|AN

Publication Type
JOURNAL ARTICLE
ISSN
0009-9309
Country of Publication
UNITED STATES

Record 3 from database: MEDLINE
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Title
Application of covalent affinity chromatography with thiol-disulphide interchange for determination of environmental exposition to heavy metals based on the quantitative determination of Zn-thionein from physiological human fluids by indirect method based on analysis of metal contents.
Author
Kabzinski AK
Address
University of LÆodÆz, Department of General and Inorganic Chemistry, Poland.
Source
Biomed Chromatogr, 1998 Sep, 12:5, 281-90
Abstract
Intoxication with heavy metals results in numerous poisonings and diseases. They disturb metabolism of the system, are the source of cancer, degeneration changes and others. As a result of kidney damage the urine of people exposed to heavy metals contains different low molecular weight proteins, oligopeptides and amino acids, indicating pathological changes. One of the proteins is a very specific metallopolythiopolypeptide--metallothionein (MT). Based on earlier investigations, a very good correlations has been found between the contents of metallothionein in urine and plasma and the concentration of heavy metals in the blood, urine, kidneys, liver and brain and general in level of exposition to heavy metals. The aim of our investigations was to carry out quantitative isolation of Zn-thionein (Zn-Th), in order to determine the level of exposition to heavy metals. For Zn-Th protein isolation by covalent affinity chromatography with thiol-disulphide interchange (CAC-TDI) was applied, which is a modern technique of separation of a high affinity, good repeatability and reproducibility, allowing specific isolation of the thiol-proteins CAC-TDI gel was used as a solid-phase extraction (SPE) support for preconcentration of Zn-Th protein and Zn bonded with Zn-Th from water, rine, plasma and breast milk samples. The investigations showed unfavourable effect of the support on separation of thiol proteins and good correlation between the concentration of MTs protein added to water, plasma and urine and the concentration of protein indirectly determined via atomic absorption spectrometric (AAS) method, by preconcentration on SPE support metals formerly bound with MT protein and absorbed on CAC-TDI gel and calculated from metals concentration. The present paper is a continuation of earlier experiments on quantitation of Hg-thionein and Cd-thionein in physiological fluids and homogenates.
Language of Publication
English
Unique Identifier
99004168

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MeSH Heading (Major)
Chromatography, Affinity|*MT; Disulfides|*AN; Environmental Exposure|*; Metallothionein|*AN/BL/UR; Metals, Heavy|*AN
MeSH Heading
Chromatography, Ion Exchange; Human; Milk, Human|CH; Reproducibility of Results; Sensitivity and Specificity

Publication Type
JOURNAL ARTICLE
ISSN
0269-3879
Country of Publication
ENGLAND

Record 4 from database: MEDLINE
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Title
Urinary kallikrein activity of workers exposed to lead.
Author
Boscolo P; Porcelli G; Cecchetti G; Salimei E; Iannaccone A
Address
 
Source
Br J Ind Med, 1978 Aug, 35:3, 226-9
Abstract
Two groups of men of different age ranges and with the same period of lead exposure were selected for study in a recently opened car-battery factory. Two other groups of age-matched men, not exposed to heavy metals in their work, were used as controls. Morning urines were collected from control and exposed groups for determination of urinary kallikrein activity, urinary delta-amino-levulinic acid (ALA) and lead levels. The environmental lead levels and the urinary ALA and lead values indicated that exposure in the factory was not heavy. The older group of lead-exposed workers showed greatly reduced urinary kallikrein activity compared with that of the age-matched controls. In contrast, the younger group did not show any significant alteration in urinary kallikrein excretion.
Language of Publication
English
Unique Identifier
79021509

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MeSH Heading (Major)
Kallikreins|*UR; Lead|*/UR; Occupational Medicine|*
MeSH Heading
Adult; Age Factors; Aminolevulinic Acid|UR; Environmental Exposure; Human; Male; Middle Age

Publication Type
JOURNAL ARTICLE
ISSN
0007-1072
Country of Publication
ENGLAND

Record 5 from database: MEDLINE
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Title
Aerosol metallic paints: deliberate inhalation. A study of inhalation and or ingestion of copper and zinc particles.
Author
Wilde C
Address
 
Source
Int J Addict, 1975, 10:1, 127-34
Abstract
The preliminary and limited study was made in an area where the metallic spray paints are used as an intoxicant by a significant percentage of the student-population. Laboratory tests show that individuals misusing these unique products are ingesting and/or inhaling large amounts of copper and zinc which are excreted in the urine and are possibly retained in body tissue. No previous reports have been found on this form of substance misuse, and apparently no studies have been conducted to determine the physiological effects of such an overload of heavy metals.
Language of Publication
English
Unique Identifier
75150866

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MeSH Heading (Major)
Administration, Intranasal|*; Copper|*TO/UR; Paint|*; Substance-Related Disorders|*; Zinc|*TO/UR
MeSH Heading
Adolescence; Adult; Aerosols; Coma|CI; Hallucinations|CI; Headache|CI; Human; Lung|DE; Lung Diseases|RA; Male; Nausea|CI; Peer Group; Support, U.S. Gov't, P.H.S.; Violence

Publication Type
JOURNAL ARTICLE
ISSN
0020-773X
Country of Publication
UNITED STATES

Record 6 from database: MEDLINE
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Title
Variegate porphyria and heavy metal poisoning from ingestion of "moonshine".
Author
Hughes GS Jr; Davis L
Address
 
Source
South Med J, 1983 Aug, 76:8, 1027-9
Abstract
A patient with cavitary tuberculosis, hepatic cirrhosis, bullous skin lesions over sun-exposed surfaces, disorientation, and a chronic, as well as recent, history of illicit alcohol consumption was found to have acute variegate porphyria by characteristic fecal and urinary porphyrin studies. Elevated levels of lead and arsenic were found in serum and urine without evidence of heavy metal storage in hair and liver. We suspect that the variegate porphyria was precipitated by the ingestion of heavy metals contained in illicit alcohol. In a patient with disorientation, bullous skin lesions, and a history of illicit alcohol ingestion, one must consider heavy metal intoxication and secondary porphyrin abnormalities.
Language of Publication
English
Unique Identifier
83275950

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MeSH Heading (Major)
Alcoholic Intoxication|*CO; Arsenic|BL/*PO/UR; Lead Poisoning|*CO; Porphyria|DI/*GE/PA
MeSH Heading
Aged; Alcoholism|CO; Case Report; Feces|AN; Human; Liver Cirrhosis|CO; Male; Porphyrins|AN/UR; Skin Diseases|ET

Publication Type
JOURNAL ARTICLE
ISSN
0038-4348
Country of Publication
UNITED STATES

Record 7 from database: MEDLINE
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Title
Renal tubular dysfunction in Minamata disease. Detection of renal tubular antigen and beta-2-microglobin in the urine.
Author
Iesato K; Wakashin M; Wakashin Y; Tojo S
Address
 
Source
Ann Intern Med, 1977 Jun, 86:6, 731-7
Abstract
"Minamata disease" was found among the residents along Minamata bay contaminated with the effluent from an industrial plant using mercury. The patients were suffering from various neurologic disorders primarily due to organic mercury poisoning. Evidence is described of renal tubular dysfunction associated with this disease by the immunochemical demonstration or renal tubular epithelial antigen and beta-2-microglobulin in the urine. Nineteen patients with Minamata disease and 35 diseased and healthy control subjects were examined. The contents of urinary renal tubular epithelial antigen and beta-2-microglobulin, and the ratios of these proteins to albumin in individuals with Minamata disease were significantly different from the levels in healthy control subjects (P less than 0.05) were identical to those found in patients with tubular and the values, proteinuria. These results indicate that Minamata disease is associated with renal tubular dysfunction, and also suggest that these procedures would be useful for screening the nephrotoxicity in the environmental exposure of heavy metals.
Language of Publication
English
Unique Identifier
77200071

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MeSH Heading (Major)
beta 2-Microglobulin|*UR; Antigens|*UR; Beta-Globulins|*UR; Kidney Tubules|*IM; Mercury Poisoning|IM/*UR
MeSH Heading
Adult; Aged; Albuminuria; Creatinine|UR; Epithelium|IM; Female; Human; Immunoglobulins, Light-Chain|UR; Male; Middle Age

Publication Type
JOURNAL ARTICLE
ISSN
0003-4819
Country of Publication
UNITED STATES

Record 8 from database: MEDLINE
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Title
Effects of molybdenum on the organism (a review).
Author
Lener J; Bíbr B
Address
 
Source
J Hyg Epidemiol Microbiol Immunol, 1984, 28:4, 405-19
Abstract
Molybdenum belongs to a group of essential microelements and occurs in all components of the environment. Major Mo sources for man are foods, especially vegetable, to a lesser extent drinking water. Its metabolism is primarily influenced by interaction with other metals, specifically copper and iron. In the organism it is primarily accumulated in the liver, kidneys, skin and hard tissues. In the blood it binds specifically with alpha-2-macroglobulin, in the erythrocytic membrane with spectrin; it enhances the osmotic resistance of red blood cells. From the organism it is eliminated in the urine, bile and feces. The biochemical importance of molybdenum lies in that it catalyzes the oxidation of xanthine and purine bases and the reduction of nitrates and molecular nitrogen; it is also present in the prosthetic group of flavoprotein enzymes. As shown in both epidemiological and animal studies, molybdenum ions may prevent dental caries. Long-term overexposure to Mo may produce molybdenosis (teart) in cattle. Increased exposures of humans may be primarily encountered in the foundry industry, but the toxic manifestations are invariably nonspecific, similarly as in the case of other heavy metals. Molybdenum-exposed workers may also show elevated uric acid concentrations in their blood, simultaneously with clinical symptoms resembling gout (gout-like syndrome). A similar finding may also occur among individuals living in areas characterized by elevated molybdenum and decreased copper contents in soil. The maximum allowable concentration limits established for soluble and insoluble molybdenum compounds in the workplace air have been accepted in many countries, but their values vary in a wide range. No specific exposure test for molybdenum has been developed as yet.
Language of Publication
English
Unique Identifier
85132602

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MeSH Heading (Major)
Molybdenum|*/AN/TU
MeSH Heading
Adult; Animal; Bile|ME; Child; Dental Caries|PC; Environmental Exposure; Female; Food Analysis; Human; Intestinal Absorption; Male; Nutritive Value; Sulfates|ME; Tissue Distribution; Water|AN; Xanthine Oxidase|ME

Publication Type
JOURNAL ARTICLE; REVIEW
ISSN
0022-1732
Country of Publication
CZECHOSLOVAKIA

Record 9 from database: MEDLINE
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Title
Misuse of hair analysis for nutritional assessment.
Author
Rivlin RS
Address
 
Source
Am J Med, 1983 Sep, 75:3, 489-93
Abstract
The analysis of hair for nutritional assessment has a number of potential pitfalls, which include: (1) contamination by sweat, (2) environmental contamination, (3) influence of previous beauty treatments, (4) critical dependence upon location of the hair sample, (5) paradoxic values depending upon the rate of hair growth, and (6) lack of clear definition of a normal range. The results of measuring metal concentrations in hair even under ideal circumstances may not correlate with those obtained in blood and urine. Long-term exposure to heavy metals, including lead, cadmium, arsenic, and mercury, can be readily identified by hair analysis. Little if any value is derived from a random examination of hair as the sole procedure for nutritional assessment. Nutritional recommendations should not be based on the results of hair analysis alone.
Language of Publication
English
Unique Identifier
83305834

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MeSH Heading (Major)
Copper|*AN; Hair|*AN/PA; Nutrition Disorders|*ME; Zinc|*AN/BL/UR
MeSH Heading
Cosmetics; Environment; False Positive Reactions; Female; Human; Male; Support, Non-U.S. Gov't; Support, U.S. Gov't, P.H.S.; Sweat; Toxicology

Publication Type
JOURNAL ARTICLE
ISSN
0002-9343
Country of Publication
UNITED STATES

Record 10 from database: MEDLINE
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Title
Mercury in urine.--Sex, age and geographic differences in a reference population.
Author
Lie A; Gundersen N; Korsgaard KJ
Address
 
Source
Scand J Work Environ Health, 1982 Jun, 8:2, 129-33
Abstract
The urine of 103 inhabitants from Hadeland and 240 persons from Odda, Norway, was examined with respect to the content of mercury and creatinine. Odda is a small community in a narrow fiord on the western coast of Norway. The sea water is polluted with mercury and other heavy metals emitted from a zinc smelter. Hadeland is a less industrialized county in the eastern part of Norway without any known inorganic mercury contamination of the external environment. None of the participants of the study were occupationally exposed to mercury. The mercury excretion was significantly higher among people living in Odda and highest among those living close to the zinc smelter. This finding probably reflects a contamination of the external environment. Women in Odda and Hadeland had a higher mercury excretion than the males of the respective regions. Mercury excretion also seemed to be age-dependent in that there was a gradual reduction in mercury excretion with advancing age. Although there seem to be age- and sex-dependent differences with respect to mercury excretion, 100 nmol of mercury/1 of urine and 10 nmol of mercury/mmol of creatinine are suggested as upper limits for "normal" mercury excretion among non-occupationally exposed persons living in Norway.
Language of Publication
English
Unique Identifier
83041216

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MeSH Heading (Major)
Environmental Pollutants|*; Mercury|*UR
MeSH Heading
Adolescence; Adult; Age Factors; Aged; Chemical Industry; Child; Child, Preschool; Comparative Study; Female; Human; Male; Middle Age; Norway; Rural Population; Sex Factors; Urban Population

Publication Type
JOURNAL ARTICLE
Country of Publication
FINLAND

Record 11 from database: MEDLINE
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Title
Analysis of submicrogramme levels of cadmium in whole blood, urine and hair by graphite furnace atomic absorption spectroscopy.
Author
Sharma RP; McKenzie JM; Kjellstrom T
Address
 
Source
J Anal Toxicol, 1982 May, 6:3, 135-8
Abstract
Toxicological studies require the analysis of heavy metals in many widely differing samples. In this paper, a simple and accurate method is described for the determination of cadmium in whole blood, urine, and hair. The blood and urine samples were digested in nitric acid at 70 degrees C, and the hair was digested in a 1:1 mixture of nitric and sulphuric acid. Altho