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New non-invasive MRA technique to view arteries

by Karl Loren

Ultrasound & Heart Disease

 

New non-invasive MRA technique to view arteries

Commentary

MRI (magnetic resonance imaging) is a powerful,  non-invasive technique used to examine the body. Each type of tissue has a specific profile which is readable by the MRI machine. The technique helps doctors observe the heart's anatomy in people with complex congenital heart disease and different types of cardiomyopathies.  It is also excellent for inspecting the pericardial sac surrounding the heart, and allows physicians to check for thickening and fluid build-up.
 
MRI can also be used to assess the function of heart valves; however,  because it is difficult to distinguish heart tissue from blood vessels, MRI has been limited to use in examining blood vessels and coronary arteries. For this reason, it has only been used to look at large vessels when diagnosing coronary artery disease.

The new MRA technique  may help refine images of tissues, making it possible in the future to diagnose coronary artery disease without an angiogram. However, angiograms will still be required to correct arterial blockages.

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(11/4/99 HeartInfo) - Having coronary arteries examined for life-threatening blockages may be easier and less invasive in the near future. Researchers are refining a 30-minute, non-invasive test called three-dimensional (3-D) coronary magnetic resonance angiography (MRA). Much like an MRI, it uses magnets to create images of arteries, report Dr. René M. Botnar and colleagues of Beth Israel Deaconess Medical Center in Boston, Mass. 

Previously, MRA created images that were not as clear and detailed as the researchers needed. Also, patients had to hold their breath during parts of the procedure.

Researchers measured the ability of tiny molecular magnets to distinguish between blood and heart tissue, allowing them to examine blood vessels. The efforts paid off. When testing the original and the improved versions of MRA on eight healthy adults and five coronary artery disease patients, researchers found the changes produced high quality images without requiring patients to hold their breath, they report in the June 22 Circulation.

The new MRA technique can also help doctors evaluate the anatomy, contractility (heart function), and valvular function of the heart, researchers report.

If approved by the Food and Drug Administration, MRA will be used with traditional angiography, a procedure in which dye is injected into blood vessels in order to X-ray them. The procedure can cause infection, bleeding, and in rare cases, heart attack and stroke.



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